[HTML][HTML] Blood-brain barrier dysfunction mediated by the EZH2-Claudin-5 axis drives stress-induced TNF-α infiltration and depression-like behaviors

ZW Sun, X Wang, Y Zhao, ZX Sun, YH Wu, H Hu… - Brain, Behavior, and …, 2024 - Elsevier
Growing evidence suggests that neurovascular dysfunction characterized by blood–brain
barrier (BBB) breakdown underlies the development of psychiatric disorders, such as major …

[HTML][HTML] Claudin-5 and occludin levels in patients with psychiatric disorders− A systematic review

Z Maridaki, G Syrros, SG Delichatsiou, J Warsh… - Brain, Behavior, and …, 2024 - Elsevier
Background Recent research has underscored the critical role of blood–brain barrier (BBB)
integrity in psychiatric disorders, highlighting disruptions in tight junction (TJ) proteins …

Vascular-related biomarkers in psychosis: a systematic review and meta-analysis

X Li, S Hu, P Liu - Frontiers in Psychiatry, 2023 - frontiersin.org
Background While the molecular underpinnings of vascular dysfunction in psychosis are
under active investigation, their implications remain unclear due to inconsistent and …

[HTML][HTML] Blood–Brain Barrier Disruption in Schizophrenia: Insights, Mechanisms, and Future Directions

F Zhang, J Zhang, X Wang, M Han, Y Fei… - International Journal of …, 2025 - mdpi.com
The blood–brain barrier (BBB) plays a crucial role in maintaining the homeostasis of the
central nervous system by regulating solute transport and preventing neurotoxic substances …

The altered network complexity of resting-state functional brain activity in schizophrenia and bipolar disorder patients

Y Niu, N Zhang, M Zhou, L Yang, J Sun… - Brain Science …, 2023 - journals.sagepub.com
Schizophrenia (SZ) and bipolar disorder (BD) are two of the most frequent mental disorders.
These disorders exhibit similar psychotic symptoms, making diagnosis challenging and …

Serum Zonulin, Claudin-5, junction Adhesion Molecule-A, Occludin and Tricellulin levels in children with autism spectrum disorder

H Eroğlu, Ü Işık, Hİ Büyükbayram… - International Journal of …, 2023 - Taylor & Francis
Introduction The aim of this study is to determine whether there is a difference in serum
Zonulin, Occludin, Claudin-5, Junctional Adhesion Molecule-A (JAM-A), Tricellulin levels …

Evaluation of SBDP145, melatonin, sLOX-1, HMGB1 and HIF-1α in preterm infants with brain injury

S Cheng, X Sun, Y Li, Y Dong - Italian Journal of Pediatrics, 2024 - Springer
Background Prematurity-related brain injury is a common and serious complication that has
long-term effects on the survival and development of affected infants. Currently, the roles of …

Serum Occludin Levels Are Elevated in Schizophrenia: A Case-Control Study

M Akkuş, PA Avşar - Neurochemical Journal, 2023 - Springer
In this study, it was aimed to compare the serum occludin levels of patients with
schizophrenia and healthy controls. There are few studies examining the relationship …