Insulin-like growth factor 2 (IGF2) emerged as a critical mechanism of synaptic plasticity and
learning and memory. Deficits in IGF2 in the brain, serum, or cerebrospinal fluid (CSF) are …

Alzheimer's disease (AD) is the most common neurodegenerative disease, which severely
threatens the health of the elderly and causes significant economic and social burdens. The …

Background Undernutrition in pregnant women is an unfavorable environmental condition
that can affect the intrauterine development via epigenetic mechanisms and thus have long …

A number of studies performed on rodents suggest that insulin-like growth factor 2 (IGF-2) or
its analogs may possibly be used for treating some conditions like Alzheimer's disease …

MicroRNAs have been demonstrated as key regulators of gene expression in the etiology of
a range of diseases including Alzheimer's disease (AD). Recently, we identified miR-483-5p …

Oxidative distress and mitochondrial dysfunction, are key factors involved in the
pathophysiology of Parkinson's disease (PD). The pleiotropic hormone insulin-like growth …

Over-activated microglia and inflammatory mediators are found in patients with depression,
while manipulation of the microglia function might represent a potential therapeutic strategy …

The Insulin-like growth factor 2 (IGF-2) has been recently proven to alleviate depressive-like
behaviors in both rats and mice models. However, its potential role as a peripheral …

Post-traumatic stress disorder (PTSD) is associated with cognitive deficits, oxidative stress,
and inflammation. Animal models have recapitulated features of PTSD, but no comparative …

Healthcare workers experienced high degree of stress during COVID-19. Purpose of the
present article is to compare mental health (depressive and Post-Traumatic-Stress …