Pancreatic islet transplantation in humans: recent progress and future directions

MR Rickels, RP Robertson - Endocrine reviews, 2019 - academic.oup.com
Pancreatic islet transplantation has become an established approach to β-cell replacement
therapy for the treatment of insulin-deficient diabetes. Recent progress in techniques for islet …

Lessons learned from more than 1,000 pancreas transplants at a single institution

DER Sutherland, RWG Gruessner, DL Dunn… - Annals of …, 2001 - journals.lww.com
Lessons Learned From More Than 1,000 Pancreas Transplants at... : Annals of Surgery Lessons
Learned From More Than 1,000 Pancreas Transplants at a Single Institution : Annals of Surgery …

Total pancreatectomy and islet autotransplantation for chronic pancreatitis

DER Sutherland, DM Radosevich, MD Bellin… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Total pancreatectomy (TP) with intraportal islet autotransplantation (IAT)
can relieve pain and preserve β-cell mass in patients with chronic pancreatitis (CP) when …

Chronic pancreatitis: current status and challenges for prevention and treatment

D Lew, E Afghani, S Pandol - Digestive diseases and sciences, 2017 - Springer
This paper reviews the current status of our understanding of the epidemiology, diagnosis,
and management of the continuum of pancreatic diseases from acute and recurrent acute …

Islet transplantation as a treatment for diabetes—a work in progress

RP Robertson - New England Journal of Medicine, 2004 - Mass Medical Soc
Although pancreas transplantation is increasingly being performed in an effort to provide
type 1 diabetic patients with the possibility of an insulin-injection–free existence, islet …

Diabetes is reversed in a murine model by marginal mass syngeneic islet transplantation using a subcutaneous cell pouch device

AR Pepper, R Pawlick, B Gala-Lopez… - …, 2015 - journals.lww.com
Background Islet transplantation is a successful β-cell replacement therapy for selected
patients with type 1 diabetes mellitus. Although high rates of early insulin independence are …

Lilly Lecture 2002: Islet transplantation: A brave new world

C Ricordi - Diabetes, 2003 - Am Diabetes Assoc
It has indeed been a distinct honor to be the recipient of the 2002 Outstanding Scientific
Achievement Award, and I was happy to accept it, on behalf of the entire islet transplant field …

International islet transplant registry report

RG Bretzel, BJ Hering, AO Schultz, C Geier… - Yearbook of Cell and …, 1996 - Springer
Long-term studies strongly suggest that tight control of blood glucose levels achieved by
conventional intensive insulin treatment, self-blood glucose monitoring and patient's …

Islet autotransplant outcomes after total pancreatectomy: a contrast to islet allograft outcomes

DER Sutherland, AC Gruessner, AM Carlson… - …, 2008 - journals.lww.com
Methods. IAT function was determined in 173 patients after total pancreatectomy at our
center. Islet function was considered full in insulin-independent patients, partial when …

[HTML][HTML] Islet xenotransplantation using gal-deficient neonatal donors improves engraftment and function

P Thompson, IR Badell, M Lowe, J Cano… - American Journal of …, 2011 - Elsevier
Significant deficiencies in understanding of xenospecific immunity have impeded the
success of preclinical trials in xenoislet transplantation. Although galactose-α1, 3-galactose …