In all domains of life, genomes contain epigenetic information superimposed over the
nucleotide sequence. Epigenetic signals control DNA–protein interactions and can cause …

Phase and antigenic variation result in a heterogenic phenotype of a clonal bacterial
population, in which individual cells either express the phase-variable protein (s) or not, or …

Strains of Staphylococcus aureus, an important human pathogen, display up to 20%
variability in their genome sequence, and most sequence information is available for human …

The amount of bacterial and archaeal genome sequence and methylome data has greatly
increased over the last decade, enabling new insights into the functional roles of DNA …

The complex relationships between infectious organisms and their hosts often reflect the
continuing struggle of the pathogen to proliferate and spread to new hosts, and the need of …

ECOLOGY The scope of mycoplasmology has been con-siderably widened during the last
few years. Not only has the total number of species been brought to over 60 (329), but …

DNA methylation is an important epigenetic mechanism for phenotypic diversification in all
forms of life. We previously described remarkable cell-to-cell heterogeneity in epigenetic …

Epigenetic modifications in bacteria, such as DNA methylation, have been shown to affect
gene regulation, thereby generating cells that are isogenic but with distinctly different …

Many bacterial species generate phenotypically heterogeneous subpopulations as a
strategy for ensuring the survival of the population as a whole–an environmental stress that …

To obtain mutants for the study of the basic biology and pathogenic mechanisms of
mycoplasmas, the insertion site of transposon Tn4001T was determined for 1700 members …