Exogenous or in situ vaccination to trigger clinical responses in pancreatic cancer

GL Beatty, EM Jaffee - Carcinogenesis, 2024 - academic.oup.com
Pancreatic ductal adenocarcinoma (PDA) is a lethal disease for which remarkable
therapeutic resistance is the norm. Conventional immunotherapies, like immune checkpoint …

Current and future immunotherapeutic approaches in pancreatic cancer treatment

P Farhangnia, H Khorramdelazad, H Nickho… - Journal of Hematology & …, 2024 - Springer
Pancreatic cancer is a major cause of cancer-related death, but despondently, the outlook
and prognosis for this resistant type of tumor have remained grim for a long time. Currently, it …

Multiplexed imaging mass cytometry analysis characterizes the vascular niche in pancreatic cancer

JH Sussman, N Kim, SB Kemp, D Traum… - Cancer …, 2024 - aacrjournals.org
Oncogenesis and progression of pancreatic ductal adenocarcinoma (PDAC) are driven by
complex interactions between the neoplastic component and the tumor microenvironment …

Emerging roles of intratumor microbiota in cancer: tumorigenesis and management strategies

Z Shi, Z Li, M Zhang - Journal of Translational Medicine, 2024 - Springer
The intricate interplay between the host and its microbiota has garnered increasing attention
in the past decade. Specifically, the emerging recognition of microorganisms within diverse …

The microbial composition of pancreatic ductal adenocarcinoma: a systematic review of 16S rRNA gene sequencing

N Merali, T Chouari, C Sweeney… - … Journal of Surgery, 2024 - journals.lww.com
Background: Pancreatic cancer, specifically pancreatic ductal adenocarcinoma (PDAC),
continues to pose a significant clinical and scientific challenge. The most significant finding …

Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct expression patterns and potential markers of progression

Y Wang, TSM Lih, JW Lee, T Ohtsuka, Y Hozaka… - bioRxiv, 2024 - biorxiv.org
In order to advance our understanding of precancers in the pancreas, 69 pancreatic
intraductal papillary neoplasms (IPNs), including 64 intraductal papillary mucinous …

[PDF][PDF] MICROBIOME IN PANCREATIC CANCER–WHAT IS NEW IN 2024?

E Hohmann, C Ammer-Herrmenau, C Schulz, S Sirtl - microbiotajournal.com
Despite great efforts to improve understanding and treatment of pancreatic cancer, mainly
pancreatic ductal adenocarcinoma (PDAC), the outcome of this malignant disease today is …