Cannabinoid receptors (CB1 and CB2), as part of the endocannabinoid system, play a
critical role in numerous human physiological and pathological conditions. Thus …

Despite low levels of cannabinoid receptor type 2 (CB2R) expression in the central nervous
system in human and rodents, a growing body of evidence shows CB2R involvement in …

Coronavirus disease (COVID-19), caused by novel severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is an ongoing pandemic and presents a public health …

The endocannabinoid system has attracted attention as a pharmacological target for several
pathological conditions. Cannabinoid (CB2)-selective agonists have been the focus of …

Recent studies have identified great similarities and interferences between the epithelial
layers of the digestive tract, the airways and the cutaneous layer. The relationship between …

The emergence of inflammatory diseases is a heavy burden on modern societies. Cannabis
has been used for several millennia to treat inflammatory disorders such as rheumatism or …

Sepsis, which is a systemic inflammatory response syndrome caused by infection, has high
morbidity and mortality. Sepsis-related liver injury is one of the manifestations of sepsis …

Acute respiratory distress syndrome (ARDS) and sepsis are risk factors contributing to
mortality in patients with pneumonia. In ARDS, also termed acute lung injury (ALI) …

Critically ill patients with sepsis require a multidisciplinary approach, as this situation implies
multiorgan distress, with most of the bodily biochemical and cellular systems being affected …

Despite extensive research, urosepsis remains a life-threatening, high-mortality disease.
Currently, animal models of urosepsis widely accepted by investigators are very scarce. This …