ADAMTS proteins are a superfamily of 26 secreted molecules comprising two related, but
distinct families. ADAMTS proteases are zinc metalloendopeptidases, most of whose …

Bronchodilators remain the cornerstone of the treatment of airway disorders such as asthma
and chronic obstructive pulmonary disease (COPD). There is therefore considerable interest …

The majority of studies of genetic association with disease have been performed in
Europeans. This European bias has important implications for risk prediction of diseases …

Background: There are well-documented disparities in lung cancer outcomes across
populations. Lung cancer screening (LCS) has the potential to reduce lung cancer mortality …

The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …

The pathogenesis of allergic rhinitis is associated with genetic, environmental, and
epigenetic factors. Genotyping of single nucleotide polymorphisms (SNPs) is an advanced …

In asthma and allergy genetics, a trend towards a few main topics developed over the last 2
years. First, a number of studies have been published recently which focus on overlapping …

Asthma is a complex respiratory disease considered as the most common chronic condition
in children. A large genetic contribution to asthma susceptibility is predicted by the clustering …

SLC39A8 is an evolutionarily highly conserved gene that encodes the ZIP8 metal cation
transporter in all vertebrates. SLC39A8 is ubiquitously expressed, including pluripotent …

This review focuses on genome-wide association studies (GWASs) of asthma and allergic
diseases published between January 1, 2018, and June 30, 2019. During this time period …