Modulating cell signalling in vivo with magnetic nanotransducers

G Romero, J Park, F Koehler, A Pralle… - Nature Reviews …, 2022 - nature.com
Weak magnetic fields offer nearly lossless transmission of signals within biological tissue.
Magnetic nanomaterials are capable of transducing magnetic fields into a range of …

[HTML][HTML] Connectivity inference from neural recording data: Challenges, mathematical bases and research directions

IM de Abril, J Yoshimoto, K Doya - Neural Networks, 2018 - Elsevier
This article presents a review of computational methods for connectivity inference from
neural activity data derived from multi-electrode recordings or fluorescence imaging. We first …

[HTML][HTML] Efficient and accurate extraction of in vivo calcium signals from microendoscopic video data

P Zhou, SL Resendez, J Rodriguez-Romaguera… - elife, 2018 - elifesciences.org
In vivo calcium imaging through microendoscopic lenses enables imaging of previously
inaccessible neuronal populations deep within the brains of freely moving animals …

[HTML][HTML] Different neuronal activity patterns induce different gene expression programs

KM Tyssowski, NR DeStefino, JH Cho, CJ Dunn… - Neuron, 2018 - cell.com
A vast number of different neuronal activity patterns could each induce a different set of
activity-regulated genes. Mapping this coupling between activity pattern and gene induction …

Population imaging of neural activity in awake behaving mice

KD Piatkevich, S Bensussen, H Tseng, SN Shroff… - Nature, 2019 - nature.com
A longstanding goal in neuroscience has been to image membrane voltage across a
population of individual neurons in an awake, behaving mammal. Here we describe a …

[HTML][HTML] Precision calcium imaging of dense neural populations via a cell-body-targeted calcium indicator

OA Shemesh, C Linghu, KD Piatkevich, D Goodwin… - Neuron, 2020 - cell.com
Methods for one-photon fluorescent imaging of calcium dynamics can capture the activity of
hundreds of neurons across large fields of view at a low equipment complexity and cost. In …

Unique contributions of parvalbumin and cholinergic interneurons in organizing striatal networks during movement

HJ Gritton, WM Howe, MF Romano… - Nature …, 2019 - nature.com
Striatal parvalbumin (PV) and cholinergic interneurons (CHIs) are poised to play major roles
in behavior by coordinating the networks of medium spiny cells that relay motor output …

A whole-brain monosynaptic input connectome to neuron classes in mouse visual cortex

S Yao, Q Wang, KE Hirokawa, B Ouellette… - Nature …, 2023 - nature.com
Identification of structural connections between neurons is a prerequisite to understanding
brain function. Here we developed a pipeline to systematically map brain-wide …

Large-scale deep tissue voltage imaging with targeted-illumination confocal microscopy

S Xiao, WJ Cunningham, K Kondabolu, E Lowet… - Nature …, 2024 - nature.com
Voltage imaging with cellular specificity has been made possible by advances in genetically
encoded voltage indicators. However, the kilohertz rates required for voltage imaging lead to …

[HTML][HTML] Large-scale voltage imaging in behaving mice using targeted illumination

S Xiao, E Lowet, HJ Gritton, P Fabris, Y Wang… - Iscience, 2021 - cell.com
Recent improvements in genetically encoded voltage indicators enabled optical imaging of
action potentials and subthreshold transmembrane voltage in vivo. To perform high-speed …