Dendritic cells (DCs) are crucial in the defence against pathogens. Invading pathogens are
recognized by Toll-like receptors (TLRs) and receptors such as C-type lectins expressed on …

▪ Abstract Dendritic cells (DCs) are highly efficient antigen-presenting cells (APCs) that
collect antigen in body tissues and transport them to draining lymph nodes. Antigenic …

Mycobacterium tuberculosis represents a world-wide health risk and immunosuppression is
a particular problem in M. tuberculosis infections. Although macrophages are primarily …

Serological antibody detection tests for tuberculosis may offer the potential to improve
diagnosis. Recent meta-analyses have shown that commercially available tests have …

A direct antigen-capture ELISA based on the detection of mycobacterial lipoarabinomannan
(LAM) in unprocessed urine was evaluated for its usefulness in clinical practice. In Tanzania …

The diagnosis of tuberculosis (TB) principally rests on the sputum examination and culture.
However, the sensitivity of sputum smear for acid-fast bacteria is only≊ 50% and sputum …

Both the urine LAM and PCR for mycobacterial DNA are being evaluated in different
geographical settings. Urine LAM currently offers little utility for the diagnosis of tuberculosis …

Recent studies have shown that the recognition of lipid antigens by the immune system is
important for defence against infection and other diseases, and that lipid-specific responses …

A coagglutination technique was established for the detection of lipoarabinomannan of
Mycobacterium tuberculosis in human serum samples and evaluated for its utility in the …

This completely revised and expanded Second Edition thoroughly examines tuberculosis
from historical, theoretical, and clinical perspectives, including the most current discoveries …