Lead phytochemicals for anticancer drug development

S Singh, B Sharma, SS Kanwar, A Kumar - Frontiers in plant science, 2016 - frontiersin.org
Cancer is a serious concern at present. A large number of patients die each year due to
cancer illnesses in spite of several interventions available. Development of an effective and …

[HTML][HTML] Pharmacotherapeutic potential of phytochemicals: Implications in cancer chemoprevention and future perspectives

V Kaur, M Kumar, A Kumar, K Kaur, VS Dhillon… - Biomedicine & …, 2018 - Elsevier
Cancer is a leading cause of disease burden throughout the world. Many cancers develop
as a result of exposure to both lifestyle and environmental factors that are potentially …

Potential chemotherapeutic effect of betalain against human non‐small cell lung cancer through PI3K/Akt/mTOR signaling pathway

Z Yin, Y Yang, T Guo… - Environmental …, 2021 - Wiley Online Library
This work focuses on evaluating the therapeutic ability of betalain and its causal
mechanisms in NSCLC both in vivo and in vitro. The experimental results demonstrated that …

[HTML][HTML] Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway

KS Prabhu, AA Bhat, KS Siveen, S Kuttikrishnan… - Biomedicine & …, 2021 - Elsevier
Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug
resistance and side effects of the current treatment options. The high mortality associated …

Aqueous extract of Moringa oleifera exhibit potential anticancer activity and can be used as a possible cancer therapeutic agent: a study involving in vitro and in vivo …

D Barhoi, P Upadhaya, SN Barbhuiya… - Journal of the …, 2021 - Taylor & Francis
Objectives New cases of cancers are increasing at an alarming rate globally. It has been
hypothesized that modern cancer treatment is associated with lots of side effects and thus …

In vitro cytotoxic activity of african plants: A review

I Canga, P Vita, AI Oliveira, MÁ Castro, C Pinho - Molecules, 2022 - mdpi.com
In African countries, cancer not only is a growing problem, but also a challenge because
available funding and resources are limited. Therefore, African medicinal plants play a …

An ethnopharmacological survey of medicinal plants traditionally used for cancer treatment in the Ashanti region, Ghana

C Agyare, V Spiegler, A Asase, M Scholz… - Journal of …, 2018 - Elsevier
Aims Cancer represents a major health burden and drain on healthcare resources in the
world. The majority of the people of Africa still patronize traditional medicine for their health …

Anticancer properties of Tulbaghia violacea regulate the expression of p53-dependent mechanisms in cancer cell lines

LR Motadi, MS Choene, NN Mthembu - Scientific reports, 2020 - nature.com
Cancer is an enormous burden of disease globally. Today, more people die from cancer
than a combination of several diseases. And in females, breast and cervical malignancies …

Novel landmarks on the journey from natural products to pharmaceutical formulations: Phytochemical, biological, toxicological and computational activities of Satureja …

B Huwaimel, AS Abouzied, S Anwar… - Food and Chemical …, 2023 - Elsevier
This study examined the ethanolic extract of the Satureja hortensis L. plant's aerial parts to
describe its phytochemical makeup, biological functions, toxicity tests, and in-silico …

[HTML][HTML] Exosomes from macrophages exposed to apoptotic breast cancer cells promote breast cancer proliferation and metastasis

X Yu, Q Zhang, X Zhang, Q Han, H Li, Y Mao… - Journal of …, 2019 - ncbi.nlm.nih.gov
Exosomes have recently become the subject of increasing research interest. Interactions
between tumor and host cells via exosomes play crucial roles in the initiation, progression …