Theories for restless legs syndrome (RLS) pathogenesis include iron deficiency, dopamine
dysregulation and peripheral neuropathy. Increased prevalence of small intestinal bacterial …

The ubiquitin proteasome system (UPS) is a proteolytic machinery for the degradation of
protein substrates that are post-translationally conjugated with ubiquitin polymers through …

Obsessive-compulsive disorder (OCD) is a common, debilitating neuropsychiatric illness
with complex genetic etiology. The International OCD Foundation Genetics Collaborative …

Objective Using narrative review techniques, this paper evaluates the evidence for
separable underlying patho-mechanisms of periodic limb movements (PLMs) to separable …

Gilles de la Tourette Syndrome (TS) is a neuropsychiatric disorder that is caused by a likely
complex genetic basis, interacting with environmental factors. Just as multiple large scale …

Background The objective of this study was to determine the frequency, nature, and impact
of sleep disorders in children and adolescents with Tourette syndrome and to raise …

Objective This review focuses on the possible association between restless legs syndrome
(RLS) and movement disorders, including Parkinson disease (PD), other parkinsonian …

Tourette syndrome is a complex neurological disorder that usually becomes evident
between 4 and 18 years of age. The disorder is characterized by chronic motor and phonic …

Tourette syndrome (TS) is a complex disorder characterized by repetitive, sudden, and
involuntary movements or vocalizations, called tics. Tics usually appear in childhood, and …

Gilles de la Tourette Syndrome (TS) is a neurodevelopmental disorder marked by the
appearance of multiple involuntary motor and vocal tics. TS presents high comorbidity rates …