Comprehensive review in current developments of benzimidazole‐based medicinal chemistry

RS Keri, A Hiremathad, S Budagumpi… - Chemical biology & …, 2015 - Wiley Online Library
The properties of benzimidazole and its derivatives have been studied over more than one
hundred years. Benzimidazole derivatives are useful intermediates/subunits for the …

Zinc complexes with nitrogen donor ligands as anticancer agents

M Porchia, M Pellei, F Del Bello, C Santini - Molecules, 2020 - mdpi.com
The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …

Solvent-free heterocyclic synthesis

MAP Martins, CP Frizzo, DN Moreira, L Buriol… - Chemical …, 2009 - ACS Publications
Heterocycles form, by far, the largest of the classical divisions of organic chemistry.
Moreover, they are of immense importance not only biologically and industrially but also to …

Mild and highly efficient method for the synthesis of 2-arylbenzimidazoles and 2-arylbenzothiazoles.

K Bahrami, MM Khodaei, F Naali - The Journal of organic chemistry, 2008 - europepmc.org
A new, convenient method for the syntheses of 2-substituted benzimidazole and
benzothizole is described. Short reaction times, large-scale synthesis, easy and quick …

Green synthesis of silver nanoparticles from green algae (Botryococcus braunii) and its catalytic behavior for the synthesis of benzimidazoles

A Arya, V Mishra, TS Chundawat - Chemical Data Collections, 2019 - Elsevier
Nanoparticles are latest developing technology and received prodigious interest because it
is simple, ecofriendly, pollutant free, non-toxic, and low-cost approach. In this report we …

Synthesis of 1, 2-disubstituted benzimidazoles, 2-substituted benzimidazoles and 2-substituted benzothiazoles in SDS micelles

K Bahrami, MM Khodaei, A Nejati - Green Chemistry, 2010 - pubs.rsc.org
A practical and convenient synthetic method has been developed for the facile synthesis of
1, 2-disubstituted benzimidazoles, 2-substituted benzimidazoles and 2-substituted …

The nano-based catalyst for the synthesis of benzimidazoles

RS Keri, V Adimule, P Kendrekar, BS Sasidhar - Topics in Catalysis, 2022 - Springer
The properties of benzimidazole and its derivatives have been studied over more than one
hundred years. The benzimidazole ring is an important pharmacophore in modern drug …

Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly (ADP-ribose) polymerase

AW White, R Almassy, AH Calvert… - Journal of medicinal …, 2000 - ACS Publications
The nuclear enzyme poly (ADP-ribose) polymerase (PARP) facilitates the repair of DNA
strand breaks and is implicated in the resistance of cancer cells to certain DNA-damaging …

Synthesis, antiviral and antitumor activity of 2-substituted-5-amidino-benzimidazoles

K Starčević, M Kralj, K Ester, I Sabol, M Grce… - Bioorganic & medicinal …, 2007 - Elsevier
We have prepared a set of heterocyclic benzimidazole derivatives bearing amidino
substituents at C-5 of benzimidazole ring, by introducing various heterocyclic nuclei …

Iron (III)-catalyzed four-component coupling reaction of 1, 3-dicarbonyl compounds, amines, aldehydes, and nitroalkanes: a simple and direct synthesis of …

S Maiti, S Biswas, U Jana - The journal of organic chemistry, 2010 - ACS Publications
A simple, convenient, and multicomponent coupling strategy for the synthesis of highly
functionalized pyrroles catalyzed by iron (III) salts has been developed. This strategy …