The medial prefrontal cortex (mPFC) and its abundant connections with other brain regions
play key roles in memory, cognition, decision making, social behaviors, and mood …

The neurobiology of schizophrenia involves multiple facets of pathophysiology, ranging from
its genetic basis over changes in neurochemistry and neurophysiology, to the systemic level …

Across species, adolescence is a period of growing independence that is associated with
the maturation of cognitive, social, and affective processing. Reorganization of neural …

Most cognitive functions involving the prefrontal cortex emerge during late development.
Increasing evidence links this delayed maturation to the protracted timeline of prefrontal …

Adolescence is a highly dynamic period of development, which includes the final
organizational phases of neural maturation within the prefrontal cortex (PFC). The …

Women and men differ in disease prevalence, symptoms, and progression rates for many
psychiatric and neurological disorders. As more preclinical studies include both sexes in …

Multiple neurocognitive systems contribute simultaneously to learning. For example,
dopamine and basal ganglia (BG) systems are thought to support reinforcement learning …

The prefrontal cortex is considered as the site of multifaceted higher-order cognitive abilities.
These abilities emerge late in life long after full sensorimotor maturation, in line with the …

Emerging scientific knowledge such as the role of epigenetics and neuroplasticity—the
brain's capability to constantly rewire with every action, experience, and thought—is …

During adolescence, youth venture out, explore the wider world, and are challenged to learn
how to navigate novel and uncertain environments. We investigated how performance …