[HTML][HTML] The role of let-7 in cell differentiation and cancer
B Boyerinas, SM Park, A Hau… - Endocrine-related …, 2010 - erc.bioscientifica.com
MicroRNAs (miRNAs or miRs) are small noncoding RNAs capable of regulating gene
expression at the translational level. Current evidence suggests that a significant portion of …
expression at the translational level. Current evidence suggests that a significant portion of …
MicroRNAs: predictors and modifiers of chemo-and radiotherapy in different tumour types
R Hummel, DJ Hussey, J Haier - European journal of cancer, 2010 - Elsevier
MicroRNAs (miRNAs) represent a class of naturally occurring small non-coding RNA
molecules. They regulate gene expression at the post-transcriptional level and control …
molecules. They regulate gene expression at the post-transcriptional level and control …
MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity
E Giovannetti, N Funel, GJ Peters, M Del Chiaro… - Cancer research, 2010 - AACR
Abstract MicroRNA-21 (miR-21) was reported to be overexpressed and contributes to
invasion and gemcitabine resistance in pancreatic ductal adenocarcinoma (PDAC). The aim …
invasion and gemcitabine resistance in pancreatic ductal adenocarcinoma (PDAC). The aim …
Reduced expression of miRNA-27a modulates cisplatin resistance in bladder cancer by targeting the cystine/glutamate exchanger SLC7A11
RM Drayton, E Dudziec, S Peter, S Bertz… - Clinical cancer …, 2014 - AACR
Purpose: Resistance to cisplatin-based chemotherapy is a major obstacle to bladder cancer
treatment. We aimed to identify microRNAs (miRNA) that are dysregulated in cisplatin …
treatment. We aimed to identify microRNAs (miRNA) that are dysregulated in cisplatin …
The passenger strand, miR-21-3p, plays a role in mediating cisplatin resistance in ovarian cancer cells
Objective Ovarian cancer is the deadliest gynaecological cancer. A major contributor to the
poor survival rate is the development of chemoresistance to platinum-based therapies such …
poor survival rate is the development of chemoresistance to platinum-based therapies such …
[HTML][HTML] Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy
JR Sierra, V Cepero, S Giordano - Molecular cancer, 2010 - Springer
In recent years, tyrosine kinases (TKs) have been recognized as central players and
regulators of cancer cell proliferation, apoptosis, and angiogenesis, and are therefore …
regulators of cancer cell proliferation, apoptosis, and angiogenesis, and are therefore …
Molecular mechanisms underlying the role of microRNAs (miRNAs) in anticancer drug resistance and implications for clinical practice
E Giovannetti, A Erozenci, J Smit, R Danesi… - Critical reviews in …, 2012 - Elsevier
Drug resistance remains a major problem in the treatment of cancer patients for both
conventional chemotherapeutic and novel biological agents. Intrinsic or acquired resistance …
conventional chemotherapeutic and novel biological agents. Intrinsic or acquired resistance …
miR-142-5p enhances cisplatin-induced apoptosis in ovarian cancer cells by targeting multiple anti-apoptotic genes
Chemotherapy is the preferred treatment for advanced ovarian cancer, but the 5-year
survival rate remains low partly because of the development of drug resistance. Although it …
survival rate remains low partly because of the development of drug resistance. Although it …
[HTML][HTML] MicroRNAs as the critical regulators of Cisplatin resistance in ovarian cancer cells
M Moghbeli - Journal of ovarian research, 2021 - Springer
Background Ovarian cancer (OC) is one of the leading causes of cancer related deaths
among women. Due to the asymptomatic tumor progression and lack of efficient screening …
among women. Due to the asymptomatic tumor progression and lack of efficient screening …
[HTML][HTML] Epigenetic biomarkers in the management of ovarian cancer: current prospectives
Ovarian cancer (OC) causes significant morbidity and mortality as neither detection nor
screening of OC is currently feasible at an early stage. Difficulty to promptly diagnose OC in …
screening of OC is currently feasible at an early stage. Difficulty to promptly diagnose OC in …