Challenges and opportunities in NASH drug development
SA Harrison, AM Allen, J Dubourg, M Noureddin… - Nature medicine, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and its more severe form, nonalcoholic
steatohepatitis (NASH), represent a growing worldwide epidemic and a high unmet medical …
steatohepatitis (NASH), represent a growing worldwide epidemic and a high unmet medical …
Current therapies and new developments in NASH
Non-alcoholic steatohepatitis is becoming the most important aetiology for advanced liver
disease. There has been important progress in the field in recent years and the complexity of …
disease. There has been important progress in the field in recent years and the complexity of …
AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
ME Rinella, BA Neuschwander-Tetri, MS Siddiqui… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …
A prospective study on the prevalence of NAFLD, advanced fibrosis, cirrhosis and hepatocellular carcinoma in people with type 2 diabetes
V Ajmera, S Cepin, K Tesfai, H Hofflich, K Cadman… - Journal of …, 2023 - Elsevier
Background & Aims There are limited prospective data on patients with type 2 diabetes
mellitus (T2DM) specifically enrolled and systematically assessed for advanced fibrosis or …
mellitus (T2DM) specifically enrolled and systematically assessed for advanced fibrosis or …
Impact of non-invasive biomarkers on hepatology practice: past, present and future
Over the last two decades, there have been tremendous advances in the non-invasive
diagnosis and risk stratification of chronic liver diseases (CLDs). Non-invasive approaches …
diagnosis and risk stratification of chronic liver diseases (CLDs). Non-invasive approaches …
[PDF][PDF] Diagnosis and management of autoimmune hepatitis in adults and children: 2019 practice guidance and guidelines from the American Association for the Study …
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALF, acute liver failure; ALT, alanine aminotransferase; AMA …
autoimmune hepatitis; ALF, acute liver failure; ALT, alanine aminotransferase; AMA …
[HTML][HTML] Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: a systematic review and meta-analysis
EA Selvaraj, FE Mózes, ANA Jayaswal… - Journal of …, 2021 - Elsevier
Background and Aims Vibration-controlled transient elastography (VCTE), point shear wave
elastography (pSWE), 2-dimensional shear wave elastography (2DSWE), magnetic …
elastography (pSWE), 2-dimensional shear wave elastography (2DSWE), magnetic …
Nonalcoholic steatohepatitis: a review
Importance Nonalcoholic steatohepatitis (NASH) is the inflammatory subtype of nonalcoholic
fatty liver disease (NAFLD) and is associated with disease progression, development of …
fatty liver disease (NAFLD) and is associated with disease progression, development of …
Nonalcoholic fatty liver disease 2020: the state of the disease
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease, with a worldwide
prevalence of 25%. In the United States, NAFLD and its subtype, nonalcoholic …
prevalence of 25%. In the United States, NAFLD and its subtype, nonalcoholic …
Noninvasive assessment of liver disease in patients with nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is estimated to afflict approximately 1 billion
individuals worldwide. In a subset of NAFLD patients, who have the progressive form of …
individuals worldwide. In a subset of NAFLD patients, who have the progressive form of …