Nanomedicine is a promising strategy for improving clinical outcomes for cancer therapies, by improving drug efficacy through enhanced delivery to disease sites. It is of importance for …
X Dong, RK Brahma, C Fang, SQ Yao - Chemical science, 2022 - pubs.rsc.org
Small-molecule prodrugs have become the main toolbox to improve the unfavorable physicochemical properties of potential therapeutic compounds in contemporary anti-cancer …
Simple Summary Cancer is one of the leading causes of death globally. Several studies, efforts and treatment strategies have been put forth for the treatment of different types of …
H Zhao, J Yu, R Zhang, P Chen, H Jiang… - European journal of …, 2023 - Elsevier
The chemotherapeutic drug of doxorubicin (DOX) has witnessed widespread applications for treating various cancers. DOX-treated dying cells bear cellular modifications which allow …
Cancer remains the leading cause of death worldwide despite advances in treatment options for patients. As such, safe and effective therapeutics are required. Short peptides …
C Evrard, G Tachon, V Randrian, L Karayan-Tapon… - Cancers, 2019 - mdpi.com
Tumor DNA mismatch repair (MMR) deficiency testing is important to the identification of Lynch syndrome and decision making regarding adjuvant chemotherapy in stage II …
Reactive oxygen species (ROS)-sensitive drug delivery systems (DDS) specifically responding to altered levels of ROS in the pathological microenvironment have emerged as …
R Zhang, J Yu, Z Guo, H Jiang, C Wang - Nanoscale, 2023 - pubs.rsc.org
Camptothecin (CPT) is a cytotoxic alkaloid that attenuates the replication of cancer cells via blocking DNA topoisomerase 1. Despite its encouraging and wide-spectrum antitumour …
H Phan, V Taresco, J Penelle, B Couturaud - Biomaterials Science, 2021 - pubs.rsc.org
Stimuli-responsive amphiphilic block copolymers have emerged as promising nanocarriers for enhancing site-specific and on-demand drug release in response to a range of stimuli …