Evolution of SARS‐CoV‐2 variants of concern over a period of Delta and Omicron cocirculation, among patients hospitalized for COVID‐19 in an Italian reference …

A Mondi, I Mastrorosa, P Piselli… - Journal of Medical …, 2023 - Wiley Online Library
Despite the higher transmissibility of Omicron Variant of Concern (VOC), several reports
have suggested lower risk for hospitalization and severe outcomes compared to previous …

Treatment-Emergent Cilgavimab Resistance Was Uncommon in Vaccinated Omicron BA. 4/5 Outpatients

CEM Gruber, FG Tucci, M Rueca, V Mazzotta… - Biomolecules, 2023 - mdpi.com
Mutations in the SARS-CoV-2 Spike glycoprotein can affect monoclonal antibody efficacy.
Recent findings report the occurrence of resistant mutations in immunocompromised …

SARS-CoV-2 protein structure and sequence mutations: Evolutionary analysis and effects on virus variants

U Lomoio, B Puccio, G Tradigo, PH Guzzi, P Veltri - Plos One, 2023 - journals.plos.org
The structure and sequence of proteins strongly influence their biological functions. New
models and algorithms can help researchers in understanding how the evolution of …

Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies

Y Kim, N Maltseva, C Tesar, R Jedrzejczak, M Endres… - Iscience, 2024 - cell.com
Coronavirus nucleocapsid protein (NP) of SARS-CoV-2 plays a central role in many
functions important for virus proliferation including packaging and protecting genomic RNA …

[HTML][HTML] A Dynamic and Effective Peptide-Based Strategy for Promptly Addressing Emerging SARS-CoV-2 Variants of Concern

M Murdocca, I Romeo, G Citro, A Latini, F Centofanti… - Pharmaceuticals, 2024 - mdpi.com
Genomic surveillance based on sequencing the entire genetic code of SARS-CoV-2
involves monitoring and studying genetic changes and variations in disease-causing …

Progress of Section “Biochemistry” in 2022

CT Supuran - International Journal of Molecular Sciences, 2023 - mdpi.com
Of more than 16,400 papers published in 2022 in International Journal of Molecular
Sciences [1], around 30–35% appeared in the Biochemistry section, which is a clear sign of …

[图书][B] Exscalate4CoV: High-Performance Computing for COVID Drug Discovery

S Coletti, G Bernardi - 2023 - books.google.com
This book highlights the different aspects of the research project “E4C Horizon 2020
European Project” aimed at fighting the coronavirus by combining the best supercomputing …

Beyond the Exscalate4CoV Project: LIGATE and REMEDI4ALL Projects

C Talarico, AR Beccari, D Graziani - Exscalate4CoV: High-Performance …, 2023 - Springer
In the last 2 years, the SARS-CoV-2 (COVID-19) pandemic demonstrated that rapid
response to outbreaks with readily effective treatments represents a primary health and …