Oral Molnupiravir and Nirmatrelvir/Ritonavir for the Treatment of COVID-19: A Literature Review with a Focus on Real-World Evidence

I Karniadakis, N Mazonakis, C Tsioutis… - Infectious Disease …, 2023 - mdpi.com
Vaccines remain the cornerstone of medical prevention and are highly effective in reducing
the risk of severe disease and death due to coronavirus disease 2019 (COVID-19). In the …

The efficacy of antivirals, corticosteroids, and mAbs as acute COVID treatments in reducing the incidence of long COVID: a Systematic Review and meta-analysis

G Sun, K Lin, J Ai, W Zhang - Clinical Microbiology and Infection, 2024 - Elsevier
Background Whether treatment during acute COVID results in protective efficacy against
long COVID incidence remains unclear. Objectives To assess the relationship between …

Real-World Effectiveness Study of Nirmatrelvir-Ritonavir or Molnupiravir in Hospitalized Unvaccinated Patients with Chronic Respiratory Diseases and Moderate …

WC Kwok, TCC Tam, JCM Ho, DCL Lam… - … Journal of Chronic …, 2024 - Taylor & Francis
Introduction Nirmatrelvir-ritonavir (NMV-r) and molnupiravir (MOL) were developed as out-
patient anti-viral for mild COVID-19. There was limited data on their role in treating COVID …

Nirmatrelvir/ritonavir for COVID-19: an overview of systematic reviews

M Cruciani, I Pati, F Masiello, S Pupella… - Journal of …, 2024 - academic.oup.com
Objectives A reappraisal of the validity of the conclusions of systematic reviews (SRs)
related to nirmatrelvir/ritonavir for the treatment of COVID-19. Methods An overview of SRs …

Clinical Outcome and 7-Day Virological Clearance in High-Risk Patients with Mild–Moderate COVID-19 Treated with Molnupiravir, Nirmatrelvir/Ritonavir, or …

F Bai, T Beringheli, V Vitaletti, A Santoro, F Molà… - Infectious Diseases and …, 2024 - Springer
Introduction We compared the effectiveness and virological clearance (VC) at day 7 (T7)
post-treatment with molnupiravir, nirmatrelvir/ritonavir, and remdesivir in SARS-CoV-2 …

Safety and efficacy of Paxlovid in the treatment of adults with mild to moderate COVID-19 during the omicron epidemic: a multicentre study from China

P Li, L Huang, R Han, M Tang, G Fei… - Expert Review of Anti …, 2024 - Taylor & Francis
ABSTRACT Background Since December 2022, the Omicron variant has led to a
widespread pandemic in China. The study was to explore the safety and effectiveness of …

The Therapy of SARS-CoV-2 Infection in Children

KM Edwards - Journal of Clinical Medicine, 2023 - mdpi.com
The impact of SARS-CoV-2 infections in children has fortunately been lower than what has
been seen in adults. However, even previously healthy children have developed severe …

Effectiveness and Safety of Molnupiravir in the Intended-Use Population: an Observational Cohort Study

W Abu-Ahmad, R Arbel, YW Sagy, E Battat… - Clinical Microbiology …, 2024 - Elsevier
Objectives Previous research reported inconsistent results on the efficacy of molnupiravir in
treating COVID-19. Moreover, efficacy was not assessed in the intended-use population …

[HTML][HTML] Tixagevimab/cilgavimab prophylaxis against COVID-19 in solid organ transplant recipients: a systematic review and meta-analysis

S Khorramnia, Z Navidi, A Orandi… - Clinical …, 2024 - ncbi.nlm.nih.gov
Background Tixagevimab/cilgavimab (Tix/Cil) shows promise as a prophylactic treatment
against coronavirus disease 2019 (COVID-19) in solid organ transplant recipients (SOTRs) …

[HTML][HTML] CLINICAL EFFECTIVENESS OF CASIRIVIMAB AND IMDEVIMAB COMPARED WITH STANDARD OF CARE IN COVID-19: A SYSTEMATIC REVIEW AND …

A Orandi, M Mohajeri, M Mansouri… - Studies in Medical …, 2024 - umj.umsu.ac.ir
Background & Aims: Monoclonal antibodies cazirivimab and imdevimab are used as a
combination drug in the treatment of severe acute respiratory syndrome coronavirus-2 …