Proteostasis refers to all the processes that maintain the correct expression level, location,
folding and turnover of proteins, essential to organismal survival. Both inside cells and in …

Transforming growth factor-β-induced protein (TGFBIp), an extracellular matrix protein, is the
second most abundant protein in the corneal stroma. In this review, we summarize the …

Protein aggregation has been one of the leading triggers of various disease conditions, such
as Alzheimer's, Parkinson's and other amyloidosis. TGFBI-associated corneal dystrophies …

Studying pathogenic effects of amyloids requires homogeneous amyloidogenic peptide
samples. Recombinant production of these peptides is challenging due to their susceptibility …

Water pollution is the biggest concern among the scientific community due to the rapid
increase in the industrial sector. The photocatalytic degradation of dyes using …

The integration of deep learning approaches in biomedical research has been
transformative, enabling breakthroughs in various applications. Despite these strides, its …

Sepsis is a potentially fatal complication of infections and there are currently no effective
therapeutic options for severe sepsis. In this study, we revealed the secretion mechanism of …

Visual impairment and blindness is a major health burden worldwide, and major ocular
diseases causing visual impairment pertain to the anterior segment of the eye. Anterior …

Drugs that can treat one disease may either be detrimental or beneficial toward another due
to possible cross-interactions. Therefore, care in choosing a suitable drug for patients with …

High temperature requirement A serine peptidase 1 (HTRA1) is a serine protease involved
in an array of signaling pathways. It is also responsible for the regulation of protein …