Symptoms of alcohol withdrawal syndrome (AWS) may develop within 6–24 h after the
abrupt discontinuation or decrease of alcohol consumption. Symptoms can vary from …

Hydrocarboxylation, hydroesterification, and hydroamidation of olefins are fundamental
transformations in organic synthesis. Asymmetric processes for these transformations …

Background Intervention to achieve alcohol abstinence represents the most effective
treatment for alcohol-dependent patients with liver cirrhosis; however, anticraving drugs …

Bowen, S., Witkiewitz, K., Clifasefi, SL, Grow, J., Chawla, N., Hsu, SH, Carroll, HA, Harrop, E.,
Collins, SE, Lustyk, MK, & Larimer, ME (2014). Relative efficacy of mindfulness-based …

For more than half a century, since the beginning of formal diagnostics, our psychiatric
nosology has compartmentalized the compulsive pursuit of substance (eg, alcohol, cocaine …

This chapter presents new clinical applications of the prototypic GABA B receptor agonist
baclofen for the treatment of addiction by drugs of abuse, such as alcohol, cocaine, nicotine …

Alcohol dependence represents a chronic and relapsing disease affecting nearly 10% of the
general population both in the USA and in Europe, with a widespread burden of morbidity …

Alcohol withdrawal syndrome (AWS) can be a life-threatening condition affecting some
alcohol-dependent patients who abruptly discontinue or decrease their alcohol …

Background Limited clinical trials and case-reports yielded conflicting results regarding the
efficacy of baclofen (a GABAB agonist) in the treatment of alcohol dependence. The aim of …

Abstract γ-aminobutyric acid (GABA) is the predominant inhibitory neurotransmitter in the
brain which acts through different receptor subtypes. Metabotropic GABA B receptors are …