Mechanobiology of annulus fibrosus and nucleus pulposus cells in intervertebral discs

S Molladavoodi, J McMorran, D Gregory - Cell and Tissue Research, 2020 - Springer
Low back pain (LBP) is a chronic condition that can affect up to 80% of the global
population. It is the number one cause of disability worldwide and has enormous …

What have we learned from finite element model studies of lumbar intervertebral discs in the past four decades?

H Schmidt, F Galbusera, A Rohlmann… - Journal of …, 2013 - Elsevier
Finite element analysis is a powerful tool routinely used to study complex biological systems.
For the last four decades, the lumbar intervertebral disc has been the focus of many such …

Comparison of eight published static finite element models of the intact lumbar spine: predictive power of models improves when combined together

M Dreischarf, T Zander, A Shirazi-Adl, CM Puttlitz… - Journal of …, 2014 - Elsevier
Finite element (FE) model studies have made important contributions to our understanding
of functional biomechanics of the lumbar spine. However, if a model is used to answer …

Spine biomechanical testing methodologies: the controversy of consensus vs scientific evidence

JJ Costi, EH Ledet, GD O'Connell - JOR spine, 2021 - Wiley Online Library
Biomechanical testing methodologies for the spine have developed over the past 50 years.
During that time, there have been several paradigm shifts with respect to techniques. These …

Geometry strongly influences the response of numerical models of the lumbar spine—a probabilistic finite element analysis

F Niemeyer, HJ Wilke, H Schmidt - Journal of biomechanics, 2012 - Elsevier
Typical FE models of the human lumbar spine consider a single, fixed geometry. Such
models cannot account for potential effects of the natural variability of the spine's geometry …

On the load-sharing along the ligamentous lumbosacral spine in flexed and extended postures: Finite element study

S Naserkhaki, JL Jaremko, S Adeeb, M El-Rich - Journal of biomechanics, 2016 - Elsevier
A harmonic synergy between the load-bearing and stabilizing components of the spine is
necessary to maintain its normal function. This study aimed to investigate the load-sharing …

FEBio finite element models of the human lumbar spine

SM Finley, DS Brodke, NT Spina… - Computer methods in …, 2018 - Taylor & Francis
Finite element analysis has proven to be a viable method for assessing many structure-
function relationships in the human lumbar spine. Several validated models of the spine …

Subject-specific biomechanics of trunk: musculoskeletal scaling, internal loads and intradiscal pressure estimation

F Ghezelbash, A Shirazi-Adl, N Arjmand… - … and modeling in …, 2016 - Springer
Abstract Development of a subject-specific computational musculoskeletal trunk model
(accounting for age, sex, body weight and body height), estimation of muscle forces and …

Development and validation of lumbar spine finite element model

T Wiczenbach, L Pachocki, K Daszkiewicz… - PeerJ, 2023 - peerj.com
The functional biomechanics of the lumbar spine have been better understood by finite
element method (FEM) simulations. However, there are still areas where the behavior of soft …

Impact of material and morphological parameters on the mechanical response of the lumbar spine–a finite element sensitivity study

T Zander, M Dreischarf, AK Timm, WW Baumann… - Journal of …, 2017 - Elsevier
Finite element models are frequently used to study lumbar spinal biomechanics.
Deterministic models are used to reflect a certain configuration, including the means of …