Recent progress in the asymmetric construction of CN, CO, and CS bonds using chiral sulfinamide reagents

MC Huang, YW Chao, YM Lin, BS Wu, CT Chou… - Tetrahedron …, 2024 - Elsevier
Chiral sulfinamides have emerged as versatile tools in various asymmetric reactions,
especially in the generation of chiral amines through asymmetric Csingle bondC bond …

Recent advances in cyclization reactions via catalytic allylic substitution for the asymmetric synthesis of heterocyclic compounds

B Pan, CVS Reddy, Y Wu, L Qiu - Tetrahedron Letters, 2024 - Elsevier
The role of allylic substitution reactions is crucial in organic synthesis. Through these
reactions, the development of numerous molecular structures with a wide range of …

Synergistic Palladium/Chiral Phosphoric Acid-Catalyzed Kinetic Resolution via Stereoselective Intramolecular Substitution of Unactivated Allylic Alcohols

CT Chou, CW Lu, BS Wu, CC Tsai - The Journal of Organic …, 2023 - ACS Publications
This paper reports the kinetic resolution of racemic secondary alcohols (O-nucleophiles) via
stereoselective intramolecular allylic substitution. The reaction was enabled by synergistic …

Desymmetrization of Cyclohexadienones through Phase-Transfer-Catalyzed Stereoselective Intramolecular Aza-Michael Addition with Chiral Sulfinamide …

BS Wu, YW Chao, HS Chen… - The Journal of Organic …, 2023 - ACS Publications
This paper reports the desymmetrization of cyclohexadienones through stereoselective
intramolecular aza-Michael addition with a tethered chiral sulfinamide nucleophile. The …

Practical synthesis of isoindolines yields potent colistin potentiators for multidrug-resistant Acinetobacter baumannii

S Dutta, S Eyolfson, Y Zhu, Y Gao… - Organic & Biomolecular …, 2024 - pubs.rsc.org
An efficient and practical one-pot synthesis of isoindolines from readily available starting
materials was achieved under mild conditions by implementing an isoindole umpolung …