Mechanosensitive Piezo channels regulate cell division, cell extrusion, and cell death.
However, systems-level functions of Piezo in regulating organogenesis remain poorly …

We investigated the wing vein network topology in fruit flies and observed that the posterior
cross vein (PCV) disrupts the symmetry of the entire network. The fluidic engineering …

Insect wing vein networks facilitate blood transport with unknown haemodynamic effects on
their structures. Fruit flies have the posterior cross vein (PCV) that disrupts the symmetry of …

Model organisms such as Drosophila melanogaster are extremely well suited to performing
large-scale screens, which often require the assessment of phenotypes in a target tissue …

The development of multicellular organisms relies on a symphony of spatiotemporally
coordinated signals that regulate gene expression. G protein-coupled receptors (GPCRs) …

Scaling between specific organs and overall body size has long fascinated biologists
because they are a primary mechanism through which organismal shapes evolve. Yet, the …

Organogenesis is a complex process that relies on the integration of a diverse set of inputs
to control multiple downstream cellular processes forming a bow-tie network. Second …

Organogenesis relies on complex and dynamic cellular processes that are mediated by
genetic programs, governed by extrinsic and intrinsic signals, and are extensively …