Arachidonic acid (AA), an n‐6 essential fatty acid, is a major component of mammalian cells
and can be released by phospholipase A2. Accumulating evidence indicates that AA plays …

Simple Summary Glioblastoma multiforme is a brain tumor with a very unfavorable
prognosis, where the vast majority of patients do not survive a year after diagnosis. One line …

Abstract Monoamine oxidase A (MAO A) and heat shock protein 90 (HSP90) inhibitors have
been shown to decrease the progression of glioblastoma (GBM) and other cancers. In this …

Tumor development and progression depend on reprogramming of signaling pathways that
regulate cell metabolism. Alterations to various metabolic pathways such as glycolysis …

Cancer represents a profound challenge to healthcare systems and individuals worldwide.
The development of multiple drug resistance is a major problem in cancer therapy and can …

Glioblastoma is the most common form of primary malignant brain tumor in adults and one of
the most lethal human cancers, with high recurrence and therapy resistance. Glioblastoma …

Simple Summary This review discusses the synthesis and significance of fatty acids,
glycerophospholipids, and triacylglycerol in glioblastoma. The focus is on all enzymes …

Glioblastoma (GBM) is a highly aggressive and lethal brain tumor, with temozolomide (TMZ)
being the standard chemotherapeutic agent for its treatment. However, TMZ resistance often …

Eicosanoids are a family of bioactive lipids that play diverse roles in the normal physiology
of the brain, including neuronal signaling, synaptic plasticity, and regulation of cerebral …

Simple Summary Glioblastoma (GBM) is one of the most malignant types of central nervous
system tumor which accounts for more than 60% of all brain tumors in adults. Owing to poor …