Exploring various techniques for the chemical and biological synthesis of polymeric nanoparticles

T Pulingam, P Foroozandeh, JA Chuah, K Sudesh - Nanomaterials, 2022 - mdpi.com
Nanoparticles (NPs) have remarkable properties for delivering therapeutic drugs to the
body's targeted cells. NPs have shown to be significantly more efficient as drug delivery …

Novel technologies based on supercritical fluids for the encapsulation of food grade bioactive compounds

S Klettenhammer, G Ferrentino, K Morozova… - Foods, 2020 - mdpi.com
In recent years, the demand for nutritive, functional and healthy foods has increased. This
trend has induced the food industry to investigate novel technologies able to produce …

[HTML][HTML] Development of intranasal implantable devices for schizophrenia treatment

E Utomo, J Domínguez-Robles… - International journal of …, 2022 - Elsevier
In this work the preparation and characterisation of intranasal implants for the delivery of
risperidone (RIS) is described. The aim of this work is to develop better therapies to treat …

Nanodrug carrier based on poly (ursolic acid) with self‐anticancer activity against colorectal cancer

K Ou, X Xu, S Guan, R Zhang, X Zhang… - Advanced Functional …, 2020 - Wiley Online Library
As the second most common cause of cancer‐related death worldwide, colorectal cancer
(CRC) requires novel therapy strategies. Biodegradable polymers are used as drug carriers …

Amphotericin B Loaded Polymeric Nanoparticles for Treatment of Leishmania Infections

M Saqib, AS Ali Bhatti, NM Ahmad, N Ahmed… - Nanomaterials, 2020 - mdpi.com
Fungal infections in immune-compromised patients are an important cause of mortality and
morbidity. Amphotericin B (Amp B) is considered a powerful fungicidal drug but its clinical …

Polymeric versus lipid nanocapsules for miconazole nitrate enhanced topical delivery: in vitro and ex vivo evaluation

RS Abdel-Rashid, DA Helal, AA Alaa-Eldin… - Drug Delivery, 2022 - Taylor & Francis
Nanocapsules can be equated to other nanovesicular systems in which a drug is entrapped
in a void containing liquid core surrounded by a coat. The objective of the present study was …

Curcumin and resveratrol delivery from multi-functionalized calcium phosphate scaffold enhances biological properties

VS Chaudhari, S Bose - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Natural medicinal compounds (NMCs) can assist effectively in treating bone disorders. NMC
release kinetics from a ceramic bone tissue engineering scaffold can be tailored. However …

Optimization of bromocriptine-mesylate-loaded polycaprolactone nanoparticles coated with chitosan for nose-to-brain delivery: In vitro and in vivo studies

MM Badran, AE Alanazi, MA Ibrahim, DH Alshora… - Polymers, 2023 - mdpi.com
Bromocriptine mesylate (BM), primarily ergocryptine, is a dopamine agonist derived from
ergot alkaloids. This study aimed to formulate chitosan (CS)-coated poly ε-caprolactone …

Box–Behnken design of experiments of polycaprolactone nanoparticles loaded with irinotecan hydrochloride

BS Mahmoud, C McConville - Pharmaceutics, 2023 - mdpi.com
Background: The Box–Behnken design of experiments (BBD) is a statistical modelling
technique that allows the determination of the significant factors in developing nanoparticles …

[HTML][HTML] Cefotaxime loaded polycaprolactone based polymeric nanoparticles with antifouling properties for in-vitro drug release applications

S Javaid, NM Ahmad, A Mahmood, H Nasir, M Iqbal… - Polymers, 2021 - mdpi.com
The objective of the present study was to achieve the successful encapsulation of a
therapeutic agent to achieve antifouling functionality regarding biomedical applications …