The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy

HH Han, HM Wang, P Jangili, M Li, L Wu… - Chemical Society …, 2023 - pubs.rsc.org
Cancer remains as one of the most significant health problems, with approximately 19
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …

Recent progress in the development of fluorescent probes for imaging pathological oxidative stress

Y Geng, Z Wang, J Zhou, M Zhu, J Liu… - Chemical Society …, 2023 - pubs.rsc.org
Oxidative stress is closely related to the physiopathology of numerous diseases. Reactive
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …

Activatable fluorescent probes for in situ imaging of enzymes

X Wu, R Wang, N Kwon, H Ma, J Yoon - Chemical Society Reviews, 2022 - pubs.rsc.org
As the main biomarkers of most diseases, enzymes play fundamental but extremely critical
roles in biosystems. High-resolution studies of enzymes using activatable in situ …

Small molecule based fluorescent chemosensors for imaging the microenvironment within specific cellular regions

J Yin, L Huang, L Wu, J Li, TD James… - Chemical Society Reviews, 2021 - pubs.rsc.org
The microenvironment (local environment), including viscosity, temperature, polarity,
hypoxia, and acidic-basic status (pH), plays indispensable roles in cellular processes …

Advances in the E → Z Isomerization of Alkenes Using Small Molecule Photocatalysts

T Nevesely, M Wienhold, JJ Molloy, R Gilmour - Chemical reviews, 2021 - ACS Publications
Geometrical E→ Z alkene isomerization is intimately entwined in the historical fabric of
organic photochemistry and is enjoying a renaissance (Roth et al. Angew. Chem., Int. Ed …

On-demand modulating afterglow color of water-soluble polymers through phosphorescence FRET for multicolor security printing

H Peng, G Xie, Y Cao, L Zhang, X Yan, X Zhang… - Science …, 2022 - science.org
Developing full-color organic ultralong room temperature phosphorescence (OURTP)
materials with continuously variable afterglow emission is of considerable practical …

Caveat fluorophore: an insiders' guide to small-molecule fluorescent labels

JB Grimm, LD Lavis - Nature Methods, 2022 - nature.com
The last three decades have brought a revolution in fluorescence microscopy. The
development of new microscopes, fluorescent labels and analysis techniques has pushed …

Recent advances in multifunctional fluorescent probes for viscosity and analytes

X Yang, D Zhang, Y Ye, Y Zhao - Coordination Chemistry Reviews, 2022 - Elsevier
Viscosity has become increasingly important in biological systems, especially as a major
factor in the process of diffusion control. The abnormality of viscosity is closely related to the …

Chemical design of activatable photoacoustic probes for precise biomedical applications

Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …

Fluorescent small organic probes for biosensing

X Tian, LC Murfin, L Wu, SE Lewis, TD James - Chemical science, 2021 - pubs.rsc.org
Small-molecule based fluorescent probes are increasingly important for the detection and
imaging of biological signaling molecules due to their simplicity, high selectivity and …