Pathophysiology of benign prostatic hyperplasia and benign prostatic enlargement: a mini-review

S Madersbacher, N Sampson, Z Culig - Gerontology, 2019 - karger.com
Benign prostatic hyperplasia (BPH), benign prostatic enlargement (BPE) and lower urinary
tract symptoms (LUTS) belong to the most frequent diseases in ageing men. Beyond the 6th …

Benign prostatic hyperplasia–what do we know?

CM Devlin, MS Simms, NJ Maitland - BJU international, 2021 - Wiley Online Library
Objectives To present historical and contemporary hypotheses on the pathogenesis of
benign prostatic hyperplasia (BPH), and the potential implications for current medical …

Anoikis and EMT: lethal" liaisons" during cancer progression

Z Cao, T Livas, N Kyprianou - Critical Reviews™ in …, 2016 - dl.begellhouse.com
Anoikis is a unique mode of apoptotic cell death that occurs consequentially to insufficient
cell-matrix interactions. Resistance to anoikis is a critical contributor to tumor invasion and …

Insulin-like growth factor (IGF) axis in cancerogenesis

A Kasprzak, W Kwasniewski, A Adamek… - … Research/Reviews in …, 2017 - Elsevier
Determination of the role of insulin-like growth factor (IGF) family components in
carcinogenesis of several human tumors is based on numerous epidemiological and pre …

Endocrine control of benign prostatic hyperplasia

S La Vignera, RA Condorelli, GI Russo, G Morgia… - …, 2016 - Wiley Online Library
Benign prostatic hyperplasia (BPH) is the most common benign proliferative disease among
aging men. Androgens play a key role in the development and growth of the male genital …

A novel insight into the immune-related interaction of inflammatory cytokines in Benign prostatic hyperplasia

X Naiyila, J Li, Y Huang, B Chen, M Zhu, J Li… - Journal of Clinical …, 2023 - mdpi.com
Benign prostatic hyperplasia (BPH) is a common male condition that impacts many men's
quality of life by generating lower urinary tract symptoms (LUTS). In recent years …

A dynamic transcriptome map of different tissue microenvironment cells identified during gastric cancer development using single-cell RNA sequencing

H Yin, R Guo, H Zhang, S Liu, Y Gong… - Frontiers in …, 2021 - frontiersin.org
Gastric cancer (GC) development trends have identified multiple processes ranging from
inflammation to carcinogenesis, however, key pathogenic mechanisms remain unclear …

Hyperglycemia and insulin resistance and the risk of BPH/LUTS: an update of recent literature

BN Breyer, AV Sarma - Current urology reports, 2014 - Springer
Benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms (LUTS) are
highly prevalent in older men and represent a substantial challenge to public health …

Phosphodiesterase type 5 inhibitor tadalafil reduces prostatic fibrosis via MiR-3126-3p/FGF9 axis in benign prostatic hyperplasia

T Li, Y Zhang, Z Zhou, L Guan, Y Zhang, Z Zhou… - Biology Direct, 2024 - Springer
Myofibroblast buildup and prostatic fibrosis play a crucial role in the development of benign
prostatic hyperplasia (BPH). Treatments specifically targeting myofibroblasts could be a …

Y-27632 targeting ROCK1&2 modulates cell growth, fibrosis and epithelial-mesenchymal transition in hyperplastic prostate by inhibiting β-catenin pathway

S Shan, M Su, H Wang, F Guo, Y Li, Y Zhou, H Liu… - Molecular …, 2024 - Springer
Benign prostatic hyperplasia (BPH) is a prevalent condition affecting the male urinary
system, with its molecular mechanisms of pathogenesis remaining unclear. Y-27632, a non …