The main inherited cardiac arrhythmias are long QT syndrome, short QT syndrome,
catecholaminergic polymorphic ventricular tachycardia and Brugada syndrome. These rare …

Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …

This international multidisciplinary document intends to provide clinicians with evidence-
based practical patient-centered recommendations for evaluating patients and decedents …

Purpose Genetic testing has advanced significantly since the publication of the 2011
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …

Background The knowledge gap regarding whether the correlation between atrial fibrillation
(AF) and dementia in observational studies is causation or driven by other shared risk …

Health care is transitioning from genetics to genomics, in which single-gene testing for
diagnosis is being replaced by multi-gene panels, genome-wide sequencing, and other …

Background: Type 1 long QT syndrome (LQT1) is caused by loss-of-function variants in the
KCNQ1-encoded Kv7. 1 potassium channel α-subunit that is essential for cardiac …

Abnormalities of ventricular action potential cause malignant cardiac arrhythmias and
sudden cardiac death. Here, we aim to identify microRNAs that regulate the human cardiac …

Importance Postmortem genetic testing of young individuals with sudden death has
previously identified pathogenic gene variants. However, prior studies primarily considered …

The primary electrical disorders are a group of inherited cardiac ventricular arrhythmias that
are a major cause of sudden cardiac death in young individuals. Inherited ventricular …