DNA methylation: an epigenetic mark of cellular memory
M Kim, J Costello - Experimental & molecular medicine, 2017 - nature.com
DNA methylation is a stable epigenetic mark that can be inherited through multiple cell
divisions. During development and cell differentiation, DNA methylation is dynamic, but …
divisions. During development and cell differentiation, DNA methylation is dynamic, but …
The role of the PI3K/Akt/mTOR signalling pathway in human cancers induced by infection with human papillomaviruses
L Zhang, J Wu, MT Ling, L Zhao, KN Zhao - Molecular cancer, 2015 - Springer
Abstract Infection with Human papillomaviruses (HPVs) leads to the development of a wide-
range of cancers, accounting for 5% of all human cancers. A prominent example is cervical …
range of cancers, accounting for 5% of all human cancers. A prominent example is cervical …
Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging
F Miura, Y Enomoto, R Dairiki, T Ito - Nucleic acids research, 2012 - academic.oup.com
DNA methylation plays a key role in epigenetic regulation of eukaryotic genomes. Hence the
genome-wide distribution of 5-methylcytosine, or the methylome, has been attracting intense …
genome-wide distribution of 5-methylcytosine, or the methylome, has been attracting intense …
Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins
Despite extensive studies on mammalian neurogenesis, its post-transcriptional regulation
remains under-explored. Here we report that neural-specific inactivation of two murine post …
remains under-explored. Here we report that neural-specific inactivation of two murine post …
Proneural genes in neocortical development
G Wilkinson, D Dennis, C Schuurmans - Neuroscience, 2013 - Elsevier
Neurons, astrocytes and oligodendrocytes arise from CNS progenitor cells at defined times
and locations during development, with transcription factors serving as key determinants of …
and locations during development, with transcription factors serving as key determinants of …
Neural stem cell niches in health and diseases
Presence of neural stem cells in adult mammalian brains, including human, has been clearly
demonstrated by several studies. The functional significance of adult neurogenesis is slowly …
demonstrated by several studies. The functional significance of adult neurogenesis is slowly …
Dynamic DNA methylation in the brain: a new epigenetic mark for experience-dependent plasticity
Experience-dependent plasticity is the ability of brain circuits to undergo molecular,
structural and functional changes as a function of neural activity. Neural activity continuously …
structural and functional changes as a function of neural activity. Neural activity continuously …
Developmental changes and sex differences in DNA methylation and demethylation in hypothalamic regions of the mouse brain
ABSTRACT DNA methylation is dynamically modulated during postnatal brain development,
and plays a key role in neuronal lineage commitment. This epigenetic mark has also …
and plays a key role in neuronal lineage commitment. This epigenetic mark has also …
DOT1L-mediated murine neuronal differentiation associates with H3K79me2 accumulation and preserves SOX2-enhancer accessibility
F Ferrari, L Arrigoni, H Franz, A Izzo, L Butenko… - Nature …, 2020 - nature.com
During neuronal differentiation, the transcriptional profile and the epigenetic context of
neural committed cells is subject to significant rearrangements, but a systematic …
neural committed cells is subject to significant rearrangements, but a systematic …
Molecular mechanisms involved in the regulation of neurodevelopment by miR-124
X Gu, X Xu, C Jia, J Wang, J Zhang, Q Gao… - Molecular …, 2023 - Springer
Abstract miR-124 is a miRNA predominantly expressed in the nervous system and accounts
for more than a quarter of the total miRNAs in the brain. It regulates neurogenesis, neuronal …
for more than a quarter of the total miRNAs in the brain. It regulates neurogenesis, neuronal …