Affinity‐based drug delivery systems utilize interactions between the therapeutic drug and
the delivery system to manipulate drug loading and to control drug release. In this paper …

Gene therapy is a therapeutic approach to deliver genetic material into cells to alter their
function in entire organism. One promising form of gene delivery system (DDS) is liposomes …

A key challenge for therapeutic application of RNA interference is to efficiently deliver
synthetic small interfering RNAs (siRNAs) into target cells that will lead to the knockdown of …

Potential clinical applications of small interfering RNA (siRNA) are hampered primarily by
delivery issues. We have successfully addressed the delivery problems associated with off …

Highly pathogenic avian influenza virus (HPAIV) of subtype H5N1 causes a devastating
disease in poultry but when it accidentally infects humans it can cause death. Therefore …

Purpose The aim of present investigation was to effectively deliver ribonucleotide reductase
subunit 1 (RRM1) targeted siRNA and assess chemo-sensitization of lung cancer cells …

HIV vaccine strategies which employ pseudovirions (PVs) as the source of antigen require
large amounts of particles. These are typically generated by transient transfection of …

RNA interference (RNAi) involves sequence-specific downregulation of target genes,
leading to gene silencing in vitro and in vivo. Synthetic small interfering RNAs (siRNAs) …

Influenza viruses are etiological agents of deadly flu that continue to pose global health
threats, and have caused global pandemics that killed millions of people worldwide. The …

Influenza A virus, the only orthomyxovirus known to infect birds, are negative-sense, single-
stranded, enveloped viruses contain genomes composed of eight separate ribonucleic acid …