Diabetic cardiomyopathy (DCM), a main cardiovascular complication of diabetes, can
eventually develop into heart failure and affect the prognosis of patients. Myocardial fibrosis …

The Aloe species is known for its medicinal and cosmetic properties. Aloin is an active
ingredient found in the leaves of medicinal plants of the genus Aloe. Aloin has attracted …

Aim: Inflammation and fibrosis have been shown to be critical factors in heart failure (HF)
progression. Calycosin (Cal) is the major active component of Astragalus mongholicus …

Myocardial fibrosis is a concomitant bioprocess associated with many cardiovascular
diseases (CVDs). Daidzein is an isoflavone that has been used for the treatment of CVDs …

Abstract Ethnopharmacological relevance Optimized New Shengmai Powder (ONSMP) is a
traditional Chinese medicine (TCM) formula for heart failure treatment. MAPK signaling …

There are several conditions that lead to female infertility, where traditional or conventional
treatments have limited efficacy. In these challenging scenarios, stem cell (SC) therapies …

Umbilical cord mesenchymal stem cells (UCMSCs) are regarded as an ideal source for
clinical use. Increasing evidence has suggested that microRNAs (miRNAs) work as a crucial …

Background Marfan syndrome (MFS) is a genetic disorder caused by mutations in fibrillin-1
and is characterized by thoracic aortic aneurysms and other complications. Previous studies …

Background Fibrosis is a tissue damage repair response caused by multiple pathogenic
factors which could occur in almost every apparatus and leading to the tissue structure …

Myocardial fibrosis is a significant pathological basis of heart failure. Overactivation of the
ERK1/2 and JNK1/2 signaling pathways of MAPK family members synergistically promotes …