The role of calmodulin in tumor cell migration, invasiveness, and metastasis

A Villalobo, MW Berchtold - International Journal of Molecular Sciences, 2020 - mdpi.com
Calmodulin (CaM) is the principal Ca2+ sensor protein in all eukaryotic cells, that upon
binding to target proteins transduces signals encoded by global or subcellular-specific …

Somatostatin and Somatostatin Receptors in Tumour Biology

U Kumar - International Journal of Molecular Sciences, 2023 - mdpi.com
Somatostatin (SST), a growth hormone inhibitory peptide, is expressed in endocrine and
non-endocrine tissues, immune cells and the central nervous system (CNS). Post-release …

Glioma synapses recruit mechanisms of adaptive plasticity

KR Taylor, T Barron, A Hui, A Spitzer, B Yalçin, AE Ivec… - Nature, 2023 - nature.com
The role of the nervous system in the regulation of cancer is increasingly appreciated. In
gliomas, neuronal activity drives tumour progression through paracrine signalling factors …

GABA regulates electrical activity and tumor initiation in melanoma

M Tagore, E Hergenreder, SC Perlee, NM Cruz… - Cancer Discovery, 2023 - AACR
Oncogenes can initiate tumors only in certain cellular contexts, which is referred to as
oncogenic competence. In melanoma, whether cells in the microenvironment can endow …

Bioactive lipids in age-related disorders

UN Das - Reviews on new drug targets in age-related disorders, 2020 - Springer
Our own studies and those of others have shown that defects in essential fatty acid (EFA)
metabolism occurs in age-related disorders such as obesity, type 2 diabetes mellitus …

DNA nanostructures for exploring cell–cell communication

Y Wang, Y Xiong, K Shi, CY Effah, L Song… - Chemical Society …, 2024 - pubs.rsc.org
The process of coordinating between the same or multiple types of cells to jointly execute
various instructions in a controlled and carefully regulated environment is a very appealing …

Tumor microenvironment and exosomes in brain metastasis: Molecular mechanisms and clinical application

Y Aili, N Maimaitiming, H Qin, W Ji, G Fan… - Frontiers in …, 2022 - frontiersin.org
Metastasis is one of the important biological features of malignant tumors and one of the
main factors responsible for poor prognosis. Although the widespread application of newer …

Neuroscience of cancer: unraveling the complex interplay between the nervous system, the tumor and the tumor immune microenvironment

Q Huang, B Hu, P Zhang, Y Yuan, S Yue, X Chen… - Molecular Cancer, 2025 - Springer
The study of the multifaceted interactions between neuroscience and cancer is an emerging
field with significant implications for understanding tumor biology and the innovation in …

A four-DNA methylation signature as a novel prognostic biomarker for survival of patients with gastric cancer

C Li, Y Zheng, K Pu, D Zhao, Y Wang, Q Guan… - Cancer Cell …, 2020 - Springer
Background Gastric cancer (GC) is the fifth most frequently diagnosed cancer and the third
leading cause of cancer-related mortality. Lack of prognostic indicators for patient survival …

Magnetic nanomaterials mediate electromagnetic stimulations of nerves for applications in stem cell and cancer treatments

L Wang, Y Duan, S Lu, J Sun - Journal of Functional Biomaterials, 2023 - mdpi.com
Although some progress has been made in the treatment of cancer, challenges remain. In
recent years, advancements in nanotechnology and stem cell therapy have provided new …