This article is part of a Special Issue" Hormones & Neurotrauma". Numerous studies aimed
at identifying the role of estrogen on the brain have used the ovariectomized rodent as the …

Progesterone is essential for pregnancy maintenance and menstrual cycle regulation.
Hormone action has been primarily ascribed to the well-characterized classical signaling …

The recent discovery of a novel, membrane localized progestin receptor (mPR) unrelated to
the classical progesterone receptor (PR) in fishes and its subsequent identification in …

Progesterone has been shown to exert pleiotropic actions in the brain of both male and
females. In particular, after traumatic brain injury (TBI), progesterone has important …

Progesterone is a gonadal steroid hormone whose physiological effects extend well beyond
the strict confines of reproductive function. In fact, progesterone can have important effects …

Introduction: The progesterone receptor plays an essential role in uterine physiology and
reproduction. Selective progesterone receptor modulators (SPRMs) have emerged as a …

Progesterone (P4) regulates a wide range of neural functions and likely acts through
multiple receptors. Over the past 30 years, most studies investigating neural effects of P4 …

The neuroactive steroids 17β-estradiol and progesterone control a broad spectrum of neural
functions. Besides their roles in the regulation of classical neuroendocrine loops, they …

Progesterone (P4) is cytoprotective in various experimental models, but our understanding
of the mechanisms involved is still incomplete. Our laboratory has implicated brain-derived …

Steroid hormone, progesterone, modulates neuroendocrine functions in the central nervous
system resulting in alterations in physiology and behavior. These neuronal effects are …