Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …

Many active pharmaceutical ingredients show low oral bioavailability due to factors such as
poor solubility and physical and chemical instability. The formation of inclusion complexes …

Cannabidiol (CBD), which has a wide variety of biological activities, is one of the
phytocannabinoids from Cannabis sativa L. However, due to the poor aqueous solubility, its …

Fucoxanthin (Fx) possesses multiple bioactivities such as antitumor, antioxidant and anti-
inflammatory activities, but its application is limited due to the poor water solubility, low …

Background: Flavonoids, a group of natural dietary polyphenols, are known for their
beneficial effects on human health. By virtue of their various pharmacological effects, like …

Implants and prostheses are widely used to replace damaged tissues or to treat various
diseases. However, besides the risk of bacterial or fungal infection, an inflammatory …

Neurodegenerative diseases such as Parkinson's disease (PD) are known to be related to
oxidative stress and neuroinflammation, and thus, modulating neuroinflammation offers a …

Flavonoids represent polyphenolic plant secondary metabolites with a general structure of a
15-carbon skeleton comprising two phenyl rings and a heterocyclic ring. Over 5000 natural …

Encapsulation of bioactive compounds s been considered a promising tool for preserving
these compounds. Several studies on dietary sources and health benefits of flavonoids, their …

Cyclodextrins (CDs) have been discovered to provide an efficient solution to the limited
application of ester aroma molecules used in food, tobacco, and medication due to their …