A review of the regulatory mechanisms of extracellular vesicles-mediated intercellular communication

YJ Liu, C Wang - Cell Communication and Signaling, 2023 - Springer
Extracellular vesicles (EVs) are small, membrane-bound structures that are released from
cells into the surrounding environment. These structures can be categorized as exosomes …

Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate

L Ginini, S Billan, E Fridman, Z Gil - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …

A guide to mass spectrometric analysis of extracellular vesicle proteins for biomarker discovery

I Jalaludin, DM Lubman, J Kim - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Exosomes (small extracellular vesicles) in living organisms play an important role in
processes such as cell proliferation or intercellular communication. Recently, exosomes …

Acquired and intrinsic gemcitabine resistance in pancreatic cancer therapy: Environmental factors, molecular profile and drug/nanotherapeutic approaches

M Ashrafizadeh, K Luo, W Zhang, AR Aref… - Environmental research, 2023 - Elsevier
A high number of cancer patients around the world rely on gemcitabine (GEM) for
chemotherapy. During local metastasis of cancers, surgery is beneficial for therapy, but …

[HTML][HTML] Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications

V Vrablova, N Kosutova, A Blsakova, A Bertokova… - Biotechnology …, 2023 - Elsevier
This review provides a comprehensive overview of our understanding of the role that
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …

Dual-Recognition Triggered Proximity Ligation Combined with a Rolling Circle Amplification Strategy for Analysis of Exosomal Protein-Specific Glycosylation

L Xu, S Lu, H Wang, H Xu, BC Ye - Analytical Chemistry, 2023 - ACS Publications
Exosomal surface glycan reveals the biological function and molecular information on the
protein, especially in indicating the pathogenesis of certain diseases through monitoring of …

Microfluidic strategies for Extracellular Vesicle isolation: towards clinical applications

A Meggiolaro, V Moccia, P Brun, M Pierno, G Mistura… - Biosensors, 2022 - mdpi.com
Extracellular vesicles (EVs) are double-layered lipid membrane vesicles released by cells.
Currently, EVs are attracting a lot of attention in the biological and medical fields due to their …

Microfluidics‐based molecular profiling of tumor‐derived exosomes for liquid biopsy

Y Wang, S Wang, L Li, Y Zou, B Liu, X Fang - View, 2023 - Wiley Online Library
Exosomes are extracellular vesicles that actively secreted by most live cells via endosome
pathway. They distribute ubiquitously in body fluids and play important roles in physiological …

Quantification of GPC1 (+) Exosomes Based on MALDI-TOF MS In Situ Signal Amplification for Pancreatic Cancer Discrimination and Evaluation

S Yan, H Zheng, J Zhao, M Gao, X Zhang - Analytical Chemistry, 2023 - ACS Publications
Pancreatic cancer (PC) has a high mortality, with a fairly low five-year survival rate, because
of its delayed diagnosis. Recently, liquid biopsy, especially based on exosomes, has …

[HTML][HTML] The hidden potential of glycomarkers: Glycosylation studies in the service of cancer diagnosis and treatment

K Grzesik, M Janik, D Hoja-Łukowicz - Biochimica et Biophysica Acta (BBA) …, 2023 - Elsevier
Abstract Changes in the glycosylation process appear early in carcinogenesis and evolve
with the growth and spread of cancer. The correlation of the characteristic glycosylation …