Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas

MJ van den Bent, JS Wefel, D Schiff… - The lancet …, 2011 - thelancet.com
Although low-grade gliomas (LGG) have a less aggressive course than do high-grade
gliomas, the outcome of these tumours is ultimately fatal in most patients. Both the tumour …

Low-grade gliomas in adults: a review

N Sanai, S Chang, MS Berger - Journal of neurosurgery, 2011 - thejns.org
In recent years, advances in the understanding of low-grade glioma (LGG) biology have
driven new paradigms in molecular markers, diagnostic imaging, operative techniques and …

[HTML][HTML] Surgical resection versus watchful waiting in low-grade gliomas

AS Jakola, AJ Skjulsvik, KS Myrmel, K Sjåvik… - Annals of …, 2017 - Elsevier
Background Infiltrating low-grade gliomas (LGG; WHO grade 2) typically present with
seizures in young adults. LGGs grow continuously and usually transform to higher grade of …

Spontaneous and therapeutic prognostic factors in adult hemispheric World Health Organization Grade II gliomas: a series of 1097 cases

L Capelle, D Fontaine, E Mandonnet… - Journal of …, 2013 - thejns.org
Object The spontaneous prognostic factors and optimal therapeutic strategy for WHO Grade
II gliomas (GIIGs) have yet to be unanimously defined. Specifically, the role of resection is …

Epileptic seizures in diffuse low-grade gliomas in adults

J Pallud, E Audureau, M Blonski, N Sanai, L Bauchet… - Brain, 2014 - academic.oup.com
Diffuse low-grade gliomas are highly epileptogenic brain tumours. We aimed to explore the
natural course of epileptic seizures, their predictors and the prognostic significance of their …

Universal scaling laws rule explosive growth in human cancers

VM Pérez-García, GF Calvo, JJ Bosque… - Nature physics, 2020 - nature.com
Most physical and other natural systems are complex entities that are composed of a large
number of interacting individual elements. It is a surprising fact that they often obey the so …

Quantifying the Role of Angiogenesis in Malignant Progression of Gliomas: In Silico Modeling Integrates Imaging and Histology

KR Swanson, RC Rockne, J Claridge, MA Chaplain… - Cancer research, 2011 - AACR
Gliomas are uniformly fatal forms of primary brain neoplasms that vary from low-to high-
grade (glioblastoma). Whereas low-grade gliomas are weakly angiogenic, glioblastomas …

The “onco-functional balance” in surgery for diffuse low-grade glioma: integrating the extent of resection with quality of life

H Duffau, E Mandonnet - Acta neurochirurgica, 2013 - Springer
Diffuse low-grade glioma (DLGG) is a growing pre-cancerous tumor, often diagnosed in
patients with no or only mild deficit. Maximal and early surgical resection is currently the first …

A mathematical modelling tool for predicting survival of individual patients following resection of glioblastoma: a proof of principle

KR Swanson, RC Rostomily, EC Alvord - British journal of cancer, 2008 - nature.com
The prediction of the outcome of individual patients with glioblastoma would be of great
significance for monitoring responses to therapy. We hypothesise that, although a large …

Prognostic significance of growth kinetics in newly diagnosed glioblastomas revealed by combining serial imaging with a novel biomathematical model

CH Wang, JK Rockhill, M Mrugala, DL Peacock, A Lai… - Cancer research, 2009 - AACR
Glioblastomas are the most aggressive primary brain tumors, characterized by their rapid
proliferation and diffuse infiltration of the brain tissue. Survival patterns in patients with …