Nuclear Factor Kappa B (NF-κB) is a ubiquitously expressed transcription factor with key
functions in a wide array of biological systems. While the role of NF-κB in processes, such as …

Neuroinflammation is initiated when glial cells, mainly microglia, are activated by threats to
the neural environment, such as pathogen infiltration or neuronal injury. Although …

In recent years, the role of B cells in neurological disorders has substantially expanded our
perspectives on mechanisms of neuroinflammation. The success of B cell-depleting …

Accurate, in-depth mapping of proteins on whole-tissue levels provides comprehensive
insights into the spatially-organized regulatory processes/networks in tissues, but is …

New neurons are continuously produced by neural stem cells (NSCs) within the adult
hippocampus. Numerous diseases, including major depressive disorder and HIV-1 …

Neuroinflammation within the central nervous system involves multiple cell types that
coordinate their responses by secreting and responding to a plethora of inflammatory …

Objectives Circadian rhythm disruption (CRD) is implicated with numerous gastrointestinal
motility diseases, with the enteric nervous system (ENS) taking main responsibility for the …

Trillions of symbiotic microbial cells colonize our body, of which the larger part is present in
the human gut. These microbes play an essential role in our health and a shift in the …

Backgrounds Abnormal vertebral growth and development have been found in adolescent
idiopathic scoliosis (AIS) patients, and the proliferation and differentiation of bone …

Neural stem cells (NSCs) play an important role in neural tissue engineering because of
their capacity of self-renewal and differentiation to multiple cell lineages. The in vitro …