Alzheimer's disease: an updated overview of its genetics

J Andrade-Guerrero, A Santiago-Balmaseda… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. It is
classified as familial and sporadic. The dominant familial or autosomal presentation …

[HTML][HTML] Past, present and future of therapeutic strategies against amyloid-β peptides in Alzheimer's disease: A systematic review

D Jeremic, L Jiménez-Díaz, JD Navarro-López - Ageing research reviews, 2021 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in ageing,
affecting around 46 million people worldwide but few treatments are currently available. The …

Global estimates on the number of persons across the Alzheimer's disease continuum

A Gustavsson, N Norton, T Fast, L Frölich… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Global estimates on numbers of persons in early stages of Alzheimer's disease
(AD), including prodromal and preclinical, are lacking, yet are needed to inform policy …

Forty-hertz light stimulation does not entrain native gamma oscillations in Alzheimer's disease model mice

M Soula, A Martín-Ávila, Y Zhang, A Dhingra… - Nature …, 2023 - nature.com
There is a demand for noninvasive methods to ameliorate disease. We investigated whether
40-Hz flickering light entrains gamma oscillations and suppresses amyloid-β in the brains of …

[图书][B] Social isolation and loneliness in older adults: Opportunities for the health care system

National Academies of Sciences… - 2020 - books.google.com
Social isolation and loneliness are serious yet underappreciated public health risks that
affect a significant portion of the older adult population. Approximately one-quarter of …

Social isolation and loneliness in older adults: review and commentary of a national academies report

NJ Donovan, D Blazer - The American Journal of Geriatric Psychiatry, 2020 - Elsevier
The authors of this review both served on the National Academy of Science, Engineering,
and Medicine Committee that produced the report,“Social Isolation and Loneliness in Older …

Education and cognitive functioning across the life span

M Lövdén, L Fratiglioni, MM Glymour… - … science in the …, 2020 - journals.sagepub.com
Cognitive abilities are important predictors of educational and occupational performance,
socioeconomic attainment, health, and longevity. Declines in cognitive abilities are linked to …

How leisure activities affect health: a narrative review and multi-level theoretical framework of mechanisms of action

D Fancourt, H Aughterson, S Finn, E Walker… - The Lancet …, 2021 - thelancet.com
There is a large and growing body of evidence on the health benefits of engagement in
leisure activities (voluntary, enjoyable non-work activities, such as hobbies, arts …

Microglia modulate neurodegeneration in Alzheimer's and Parkinson's diseases

T Bartels, S De Schepper, S Hong - Science, 2020 - science.org
Dementia is a rapidly rising global health crisis that silently disables families and ends lives
and livelihoods around the world. To date, however, no early biomarkers or effective …

Assessing the mechanisms of brain plasticity by transcranial magnetic stimulation

A Jannati, LM Oberman, A Rotenberg… - …, 2023 - nature.com
Transcranial magnetic stimulation (TMS) is a non-invasive technique for focal brain
stimulation based on electromagnetic induction where a fluctuating magnetic field induces a …