Abstract Haem oxygenase 1 (HO-1), an inducible enzyme responsible for the breakdown of
haem, is primarily considered an antioxidant, and has long been overlooked by …

Heme oxygenase (HO) is the primary antioxidant enzyme involved in heme group
degradation. A variety of stimuli triggers the expression of the inducible HO-1 isoform, which …

Chimeric antigen receptor (CAR)-T cell therapy demonstrates substantial efficacy in various
hematological malignancies. However, its application in solid tumors is still limited. Clinical …

In our paper, we discuss how the early phases of ankylosing spondylitis (AS) are linked to
peri-firbocartilagenous osteitis in the sacroiliac joint and entheseal bone related anchoring …

Fumaric acid esters (FAEs) such as dimethylfumarate (DMF) are used for the treatment of
adults with moderate‐to‐severe psoriasis. The mode of action of FAEs is complex. Here, we …

Psoriasis is a common chronic inflammatory skin disease associated with several
comorbidities and reduced quality of life. In the past decades, highly effective targeted …

T helper (Th) cells producing interleukin (IL)-17, IL-22, and tumor necrosis factor (TNF) form
the key T cell population driving psoriasis pathogenesis. They orchestrate the inflammation …

Background Patients with liver cirrhosis and minimal hepatic encephalopathy (MHE) show
mild cognitive impairment and spatial learning dysfunction. Hyperammonemia acts …

Inflammatory diseases present a serious health challenge due to their widespread
prevalence and the severe impact on patients' lives. In the quest to alleviate the burden of …

Inflammation and immune responses are intricately intertwined processes crucial for
maintaining homeostasis and combating against pathogens. These processes involve …