Simple Summary Cell migration is an essential process from embryogenesis to cell death.
This is tightly regulated by numerous proteins that help in proper functioning of the cell. In …

Abstract Development of therapeutic resistance and metastasis is a major challenge with
current breast cancer (BC) therapy. Mounting evidence suggests that a subpopulation of …

Human cancer cell lines have long served as tools for cancer research and drug discovery,
but the presence and the source of intra-cell-line heterogeneity remain elusive. Here, we …

Functional studies giving insight into the biology of circulating tumor cells (CTC s) remain
scarce due to the low frequency of CTC s and lack of appropriate models. Here, we describe …

Mechanically induced signal transduction has an essential role in development. Cells
actively transduce and respond to mechanical signals and their internal architecture must …

Intermediate filament (IF) proteins make up the largest family of cytoskeletal proteins in
metazoans, and are traditionally known for their roles in fostering structural integrity in cells …

End-stage kidney disease (ESKD) patients are at high risk of severe COVID-19. We
measured 436 circulating proteins in serial blood samples from hospitalised and non …

Background Human cancer cell lines are fundamental models for cancer research and
therapeutic strategy development. However, there is no characterization of circular RNAs …

The heterogeneity of hepatocellular carcinoma (HCC) commonly leads to therapeutic failure
of HCC. Cytokeratin 19 (CK19) is well acknowledged as a biliary/progenitor cell marker and …

Initially correlated with hematopoietic precursors, the surface expression of CD133 was also
found in epithelial and nonepithelial cells from adult tissues in which it has been associated …