Gravity sensing in plant and animal cells

K Takahashi, H Takahashi, T Furuichi, M Toyota… - npj …, 2021 - nature.com
Gravity determines shape of body tissue and affects the functions of life, both in plants and
animals. The cellular response to gravity is an active process of mechanotransduction …

[HTML][HTML] Drug repurposing for the treatment of COVID-19

Y Kato, K Nishiyama, A Nishimura, T Noda… - Journal of …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) remains prevalent worldwide since its onset
was confirmed in Wuhan, China in 2019. Vaccines against the causative virus, severe acute …

Influence of the co-exposure of microplastics and tetrabromobisphenol A on human gut: Simulation in vitro with human cell Caco-2 and gut microbiota

W Huang, H Yin, Y Yang, L Jin, G Lu, Z Dang - Science of the Total …, 2021 - Elsevier
Microplastics (MPs) pollution becomes an emergent threat to the ecosystem, and its joint
effect with organic contaminants will cause more severe consequences. Recently, MPs has …

Sustained AT1R stimulation induces upregulation of growth factors in human cardiac fibroblasts via Gαq/TGF-β/ERK signaling that influences myocyte hypertrophy

R Duangrat, W Parichatikanond, NP Morales… - European Journal of …, 2022 - Elsevier
Stimulation of angiotensin II receptor (ATR) with angiotensin II (Ang II) accelerates cardiac
fibroblast activation, resulting in upregulation of cytokines and growth factors. Growth factors …

New insights into the size-independent bioactive potential of pristine and UV-B aged polyethylene microplastics

S Dailianis, M Rouni, NM Ainali, D Vlastos… - Science of the Total …, 2024 - Elsevier
The present study investigates the morphological, physicochemical, and structural changes
occurred by the UV-B aging process of low-density polyethylene microplastics (LDPE MPs) …

[HTML][HTML] Extracellular ATP facilitates cell extrusion from epithelial layers mediated by cell competition or apoptosis

Y Mori, N Shiratsuchi, N Sato, A Chaya, N Tanimura… - Current Biology, 2022 - cell.com
For the maintenance of epithelial homeostasis, various aberrant or dysfunctional cells are
actively eliminated from epithelial layers. This cell extrusion process mainly falls into two …

Stimulation of adenosine A1 receptor prevents oxidative injury in H9c2 cardiomyoblasts: Role of Gβγ-mediated Akt and ERK1/2 signaling

S Mangmool, ETH Kyaw, N Nuamnaichati… - Toxicology and Applied …, 2022 - Elsevier
Oxidative stress causes cellular injury and damage in the heart primarily through apoptosis
resulting in cardiac abnormalities such as heart failure and cardiomyopathy. During …

Sensory neuron–expressed TRPC3 mediates acute and chronic itch

Y Liu, Y Liu, N Limjunyawong, C Narang, H Jamaldeen… - Pain, 2023 - journals.lww.com
Chronic pruritus is a prominent symptom of allergic contact dermatitis (ACD) and represents
a huge unmet health problem. However, its underlying cellular and molecular mechanisms …

Cardioprotective effects of glucagon-like peptide-1 (9-36) against oxidative injury in H9c2 cardiomyoblasts: Potential role of the PI3K/Akt/NOS pathway

N Nuamnaichati, W Parichatikanond… - Journal of …, 2022 - journals.lww.com
Abstract Glucagon-like peptide (GLP)-1 (7-36), a major active form of GLP-1 hormone, is
rapidly cleaved by dipeptidyl peptidase-4 to generate a truncated metabolite, GLP-1 (9-36) …

Canonical transient receptor potential channels and vascular smooth muscle cell plasticity

M Nishida, T Tanaka, S Mangmool… - Journal of Lipid and …, 2020 - synapse.koreamed.org
Vascular smooth muscle cells (VSMCs) play a pivotal role in the stability and tonic regulation
of vascular homeostasis. VSMCs can switch back and forth between highly proliferative …