Background Posttraumatic stress disorder (PTSD) may stem from the formation of aberrant
and enduring aversive memories. Some PTSD patients have recreationally used Cannabis …

Erasing maladaptive memories has been a challenge for years. A way to change fear
memories is to target the process of reconsolidation, during which a retrieved memory …

Obesity has acquired notable attention due to its high occurrence and link with grievous
health problems such as hypertension, diabetes and heart disease. It has been reported that …

Endocannabinoid signalling mediated by cannabinoid receptor 1 (CB1R, also known as
CNR1) is critical for homeostatic neuromodulation of both excitatory and inhibitory synapses …

Introduction. Medical cannabis (MC) is becoming increasingly popular for the treatment of
chronic pain conditions. In this study, we evaluated the effect of MC treatment on pain level …

The endocannabinoid system is involved in the fine-tuning of local synaptic plasticity in the
hippocampus during the initial steps of memory formation/transformation. In spite of …

Drug-associated pathological memory remains a critical factor contributing to the
persistence of substance use disorder. Pharmacological amnestic manipulation to interfere …

Rationale Pharmacological targeting of memory reconsolidation is a promising therapeutic
strategy for the treatment of fear memory-related disorders. However, the success of …

Cannabis preparations could be an effective reconsolidation-based treatment for post-
traumatic stress disorder. However, the effects of Δ 9-tetrahydrocannabinol (THC) in fear …

Upon reactivation, consolidated memories can enter a temporary labile state and require
restabilisation, known as reconsolidation. Interventions during this reconsolidation period …