Effective regeneration of bone defects often presents significant challenges, particularly in
patients with decreased tissue regeneration capacity due to extensive trauma, disease …

Regenerative medicine literature has proposed mesenchymal stem/progenitor cell‐(MSC‐)
mediated therapeutic approaches for their great potential in managing various diseases and …

Background Autologous grafting, despite some disadvantages, is still considered the gold
standard for reconstruction of maxillofacial bone defects. The aim of this study was to …

The therapeutic potential of the dental pulp stem (DSC) cell-derived secretome, consisting of
various biomolecules, is undergoing intense research. Despite promising in vitro and in vivo …

Physiological root resorption of deciduous teeth is a normal phenomenon. How the
angiogenesis process is regulated to provide adequate levels of oxygen and nutrients in …

Oral mesenchymal stem cells (MSCs) and their secretomes are considered important factors
in the field of medical tissue engineering and cell free biotherapy due to their ease of …

Hypoxia was proved to enhance the angiogenesis of stem cells. However, the mechanism of
the angiogenic potential in hypoxia-pretreated dental pulp stem cells (DPSCs) is poorly …

For more than 20 years, researchers have isolated and identified postnatal dental pulp stem
cells (DPSCs) from different teeth, including natal teeth, exfoliated deciduous teeth, healthy …

Dental pulp stem cells (DPSCs) and their exosomes (Exos) are effective treatments for
regenerative medicine. Hypoxia was confirmed to improve the angiogenic potential of stem …

Oxidative stress from high levels of intracellular reactive oxygen species (ROS) has been
linked to various bone diseases. Previous studies indicate that mesenchymal stem cells …