Virulence Factors in Hypervirulent Klebsiella pneumoniae

J Zhu, T Wang, L Chen, H Du - Frontiers in microbiology, 2021 - frontiersin.org
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the
Asian Pacific Rim. It is an invasive variant that differs from the classical K. pneumoniae …

Klebsiella pneumoniae: going on the offense with a strong defense

MK Paczosa, J Mecsas - Microbiology and molecular biology …, 2016 - Am Soc Microbiol
Klebsiella pneumoniae causes a wide range of infections, including pneumonias, urinary
tract infections, bacteremias, and liver abscesses. Historically, K. pneumoniae has caused …

Molecular Pathogenesis of Klebsiella Pneumoniae

B Li, Y Zhao, C Liu, Z Chen, D Zhou - Future microbiology, 2014 - Taylor & Francis
Typical Klebsiella pneumoniae is an opportunistic pathogen, which mostly affects those with
weakened immune systems and tends to cause nosocomial infections. A subset of …

Hypervirulent klebsiella pneumoniae

TA Russo, CM Marr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Hypervirulent K. pneumoniae (hvKp) is an evolving pathotype that is more virulent than
classical K. pneumoniae (cKp). hvKp usually infects individuals from the community, who are …

Klebsiella pneumoniae AcrAB Efflux Pump Contributes to Antimicrobial Resistance and Virulence

E Padilla, E Llobet, A Doménech-Sánchez… - Antimicrobial agents …, 2010 - Am Soc Microbiol
Respiratory infections caused by Klebsiella pneumoniae are characterized by high rates of
mortality and morbidity. Management of these infections is often difficult, due to the high …

The making of hypervirulent Klebsiella pneumoniae

P Dai, D Hu - Journal of Clinical Laboratory Analysis, 2022 - Wiley Online Library
Klebsiella pneumoniae is a notorious bacterium in clinical practice. Virulence, carbapenem‐
resistance and their convergence among K. pneumoniae are extensively discussed in this …

[HTML][HTML] Complement resistance mechanisms of Klebsiella pneumoniae

DJ Doorduijn, SHM Rooijakkers, W van Schaik… - Immunobiology, 2016 - Elsevier
The current emergence of antibiotic-resistant bacteria causes major problems in hospitals
worldwide. To survive within the host, bacterial pathogens exploit several escape …

Clinical Implications of Genomic Adaptation and Evolution of Carbapenem-Resistant Klebsiella pneumoniae

A Gomez-Simmonds… - The Journal of infectious …, 2017 - academic.oup.com
Klebsiella pneumoniae poses a major challenge to healthcare worldwide as an important
cause of multidrug-resistant infections. Nosocomial clones, including epidemic sequence …

Identification of Klebsiella pneumoniae virulence determinants using an intranasal infection model

MS Lawlor, J Hsu, PD Rick, VL Miller - Molecular microbiology, 2005 - Wiley Online Library
Klebsiella pneumoniae is a Gram‐negative enterobacterium that has historically been, and
currently remains, a significant cause of human disease. It is a frequent cause of urinary tract …

Characterization of Klebsiella pneumoniae Type 1 Fimbriae by Detection of Phase Variation during Colonization and Infection and Impact on Virulence

C Struve, M Bojer, KA Krogfelt - Infection and immunity, 2008 - Am Soc Microbiol
Klebsiella pneumoniae is recognized as an important gram-negative opportunistic
pathogen. The ability of bacteria to adhere to host structures is considered essential for the …