Psoriatic arthritis (PsA) is part of a group of closely related clinical phenotypes ('psoriatic
disease') that is defined by shared molecular pathogenesis resulting in excessive …

The excellent clinical efficacy of anti-interleukin 17A (IL-17A) biologics on psoriasis indicates
a crucial pathogenic role of IL-17A in this autoinflammatory skin disease. IL-17A accelerates …

Central memory T (TCM) cells patrol lymph nodes and perform conventional memory
responses on restimulation: proliferation, migration and differentiation into diverse T cell …

Psoriatic arthritis (PsA), a heterogeneous chronic inflammatory immune-mediated disease
characterized by musculoskeletal inflammation (arthritis, enthesitis, spondylitis, and …

As the thymus involutes during aging, the T‐cell pool has to be maintained by the periodic
expansion of preexisting T cells during adulthood. A conundrum is that repeated episodes of …

The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A-F, plays crucial
roles in host defence against microbial organisms and the development of inflammatory …

Twenty to thirty percent of psoriasis (Pso) patients will develop psoriatic arthritis (PsA).
Detection of Pso patients that are (at risk for) developing PsA is essential to prevent …

Early diagnosis of psoriatic arthritis (PSA) is important for successful therapeutic intervention
but currently remains challenging due, in part, to the scarcity of non-invasive biomarkers. In …

CD (cluster of differentiation) 69 and CD25 are considered early and late markers of the
activation of lymphocytes, respectively. CD25 is a part of the IL-2 receptor and is present on …

Psoriatic arthritis (PsA) is a chronic inflammatory disease that affects multiple organ systems
and is characterized by skin and joint manifestations. PsA is frequently undiagnosed and/or …