The uptake, transport, and presentation of Ags by lung dendritic cells (DCs) are central to the
initiation of CD8 T cell responses against respiratory viruses. Although several studies have …

Immune responses are initiated and primed by dendritic cells (DCs) that cross-present
exogenous antigen. The chaperone CD74 (invariant chain) is thought to promote DC …

TAP1-TAP2 heterodimeric complexes are recognized as the transporter associated with
antigen processing of major histocompatibility complex class I peptides for recognition by …

Genetic and epigenetic events have been implicated in the downregulation of the cellular
antigen processing and presentation machinery (APM), which in turn, has been associated …

The transporter associated with antigen processing (TAP) and the major histocompatibility
complex class I (MHC-I), two important components of the MHC-I antigen presentation …

Surfactant protein A (SP-A) in addition to its surfactant-related functions interacts with
alveolar macrophages (AM), the guardian cells of innate immunity in the lungs, and …

Ability to cross-present exogenous antigens in the human leukocyte antigen class I pathway
is key to the antigen presenting function of mature tumor cell-loaded dendritic cells (DC) …

One of the primary obstacles in current cancer treatments lies in the extensive heterogeneity
of genetic and epigenetic changes that occur in each arising tumour. However, an additional …

As we know, prostate cancer down-regulates expression of HLA-1 Antigen Processing
Machinery (APM) and has defects in the antigen presentation pathway. In vitro, the prostate …

For eons, turmeric and curcumin have been used as culinary spices and as traditional
medicines and as vogue dietary supplements for a growing list of disorders, including …