Emergence of synthetic mRNA: In vitro synthesis of mRNA and its applications in regenerative medicine

H Kwon, M Kim, Y Seo, YS Moon, HJ Lee, K Lee, H Lee - Biomaterials, 2018 - Elsevier
The field of gene therapy has evolved over the past two decades after the first introduction of
nucleic acid drugs, such as plasmid DNA (pDNA). With the development of in vitro …

[HTML][HTML] Erythrocytes as carriers: From drug delivery to biosensors

L Koleva, E Bovt, F Ataullakhanov, E Sinauridze - Pharmaceutics, 2020 - mdpi.com
Drug delivery using natural biological carriers, especially erythrocytes, is a rapidly
developing field. Such erythrocytes can act as carriers that prolong the drug's action due to …

Red blood cell inspired strategies for drug delivery: emerging concepts and new advances

E Zhang, P Phan, HA Algarni, Z Zhao - Pharmaceutical Research, 2022 - Springer
In the past five decades, red blood cells (RBCs) have been extensively explored as drug
delivery systems due to their distinguishing potential in modulating the pharmacokinetic …

Oncolytic virotherapy in solid tumors: the challenges and achievements

KT Jin, WL Du, YY Liu, HR Lan, JX Si, XZ Mou - Cancers, 2021 - mdpi.com
Simple Summary Oncolytic virotherapy (OVT) is a promising approach in cancer
immunotherapy. Oncolytic viruses (OVs) could be applied in cancer immunotherapy without …

Rhabdoviruses as vectors for vaccines and therapeutics

G Scher, MJ Schnell - Current opinion in virology, 2020 - Elsevier
Appropriate choice of vaccine vector is crucial for effective vaccine development.
Rhabdoviral vectors, such as rabies virus and vesicular stomatitis virus, have been used in a …

Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect

R Yokoda, BM Nagalo, B Vernon, R Oklu… - Oncolytic …, 2017 - Taylor & Francis
With the advancement of a growing number of oncolytic viruses (OVs) to clinical
development, drug delivery is becoming an important barrier to overcome for optimal …

Reversible fusion proteins as a tool to enhance uptake of virus-functionalized LbL microcarriers

K Scheffler, C Claus, ML Stanifer, S Boulant… - …, 2018 - ACS Publications
For the efficient treatment of an increasing number of diseases the development of new
therapeutics as well as novel drug delivery systems is essential. Such drug delivery systems …

[PDF][PDF] VSV-G viral envelope glycoprotein prepared from Pichia pastoris enhances transfection of DNA into animal cells

X Liu, Y Dong, J Wang, L Li, Z Zhong, YP Li… - Journal of Microbiology …, 2017 - jmb.or.kr
Vesicular stomatitis virus G glycoprotein (VSV-G) has been widely used for pseudotyping
retroviral, lentiviral, and artificial viral vectors. The objective of this study was to establish a …

Development of Rhabdoviral-Based Crimean-Congo Hemorrhagic Fever Virus Vaccines

G Scher - 2023 - search.proquest.com
Abstract Crimean-Congo Hemorrhagic Fever virus (CCHFV) is an emerging, tickborne,
zoonotic virus with an expansive global distribution. CCHFV is a biosafety level 4 (BSL-4) …

Role of cell-to-cell communication in guiding breast cancer cell physiology

L Pedzisayi - 2022 - search.proquest.com
The ability of cells to communicate constitutes an important characteristic of all multi-cellular
organisms. Cells participate in a continuous relay of information between their environment …