Severe acute respiratory syndrome coronavirus 2 variants of concern: a perspective for emerging more transmissible and vaccine-resistant strains

AS de Souza, VM de Freitas Amorim, GDA Guardia… - Viruses, 2022 - mdpi.com
Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern
(VOC) are constantly threatening global public health. With no end date, the pandemic …

SARS-CoV-2 virion physicochemical characteristics pertinent to abiotic substrate attachment

Z Adamczyk, P Batys, J Barbasz - Current Opinion in Colloid & Interface …, 2021 - Elsevier
The structure, size, and main physicochemical characteristics of the SARS-CoV-2 virion with
the spike transmembrane protein corona were discussed. Using these data, diffusion …

[HTML][HTML] Effects of COVID-19 infection and vaccination on the female reproductive system: a narrative review

S Pourmasumi, NG Kounis, M Naderi… - Balkan medical …, 2023 - ncbi.nlm.nih.gov
Several studies and research papers have been published to elucidate and understand the
mechanism of the coronavirus disease 2019 (COVID-19) pandemic and its long-term effects …

In silico binding profile characterization of SARS-CoV-2 spike protein and its mutants bound to human ACE2 receptor

Y Zhang, X He, J Zhai, B Ji, VH Man… - Briefings in …, 2021 - academic.oup.com
Severe acute respiratory syndrome coronavirus (SARS-CoV-2), a novel coronavirus, has
brought an unprecedented pandemic to the world and affected over 64 million people. The …

Rational approach toward COVID-19's main protease inhibitors: A hierarchical biochemoinformatics analysis

RS Bastos, CPO de Aguiar, JN Cruz… - International Journal of …, 2024 - mdpi.com
This study investigated the potential of selected compounds as inhibitors of SARS-CoV-2
Mpro through pharmacokinetic and toxicological analyses, molecular docking, and …

Molecular level dissection of critical spike mutations in SARS‐CoV‐2 variants of concern (VOCs): a simplified review

N Joshi, A Tyagi, S Nigam - ChemistrySelect, 2021 - Wiley Online Library
SARS‐CoV‐2 virus during its spread in the last one and half year has picked up critical
changes in its genetic code ie mutations, which have leads to deleterious epidemiological …

Molecular dynamics simulations of the spike trimeric ectodomain of the SARS-CoV-2 Omicron variant: structural relationships with infectivity, evasion to immune …

AS de Souza, VMF Amorim, RF de Souza… - Journal of …, 2023 - Taylor & Francis
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron is currently
the most prevalent SARS-CoV-2 variant worldwide. Herein, we calculated molecular …

In Silico, In Vitro and In Cellulo Models for Monitoring SARS-CoV-2 Spike/Human ACE2 Complex, Viral Entry and Cell Fusion

D Lapaillerie, C Charlier, HS Fernandes, SF Sousa… - Viruses, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent
responsible for the recent coronavirus disease 2019 (COVID-19) pandemic. Productive …

Cooperative and structural relationships of the trimeric Spike with infectivity and antibody escape of the strains Delta (B. 1.617. 2) and Omicron (BA. 2, BA. 5, and BQ. 1 …

AS de Souza, RF de Souza, CR Guzzo - Journal of Computer-Aided …, 2023 - Springer
Herein, we conducted simulations of trimeric Spike from several SARS-CoV-2 variants of
concern (Delta and Omicron sub-variants BA. 2, BA. 5, and BQ. 1) and investigated the …

Molecular dynamics analysis of fast-spreading severe acute respiratory syndrome coronavirus 2 variants and their effects on the interaction with human angiotensin …

AS de Souza, VM de Freitas Amorim, GDA Guardia… - ACS …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is evolving with mutations
in the spike protein, especially in the receptor-binding domain (RBD). The failure of public …