DNA damage repair: historical perspectives, mechanistic pathways and clinical translation for targeted cancer therapy

R Huang, PK Zhou - Signal transduction and targeted therapy, 2021 - nature.com
Genomic instability is the hallmark of various cancers with the increasing accumulation of
DNA damage. The application of radiotherapy and chemotherapy in cancer treatment is …

A two-stage genome-wide association study to identify novel genetic loci associated with acute radiotherapy toxicity in nasopharyngeal carcinoma

Y Wang, F Xiao, Y Zhao, CX Mao, LL Yu, LY Wang… - Molecular Cancer, 2022 - Springer
Background Genetic variants associated with acute side effects of radiotherapy in
nasopharyngeal carcinoma (NPC) remain largely unknown. Methods We performed a two …

Single Nucleotide Polymorphisms as Biomarker Predictors of Oral Mucositis Severity in Head and Neck Cancer Patients Submitted to Combined Radiation Therapy …

R Cavalieri, HF de Oliveira, T Louvain de Souza… - Cancers, 2024 - mdpi.com
Simple Summary Single Nucleotide Polymorphisms (SNPs) are the most common type of
genetic variation found in an individual's DNA sequences. SNPs can occur in both coding …

[HTML][HTML] Systematic Review of Genetic Polymorphisms Associated with Acute Pain Induced by Radiotherapy for Head and Neck Cancers

V Salama, Y Geng, J Rigert, CD Fuller, S Shete… - Clinical and …, 2023 - Elsevier
Background/objective Pain is the most common acute symptom following radiation therapy
(RT) for head and neck cancer (HNC). The multifactorial origin of RT-induced pain makes it …

Potential Single Nucleotide Polymorphisms markers for radiation dermatitis in head and neck cancer patients: a meta-analysis

BRL Aguiar, EB Ferreira, AGC Normando… - Strahlentherapie und …, 2024 - Springer
Purpose To identify potential Single Nucleotide Polymorphisms (SNPs) of susceptibility for
the development of acute radiation dermatitis in head and neck cancer patients, and also to …

[HTML][HTML] Radiogenomics: A Personalized Strategy for Predicting Radiation-Induced Dermatitis

BRL de Aguiar, ENS Guerra, PED dos Reis - Radiation Therapy, 2022 - intechopen.com
Although radiation therapy (RT) planning and execution techniques have evolved to
minimize radiotoxicity to a considerable extent, adjacent tissues still receive a substantial …

Systematic Review of Genetic Polymorphisms Associated with Acute Pain and Relevant Acute Toxicities Induced by Radiotherapy for Head and Neck Cancer

V Salama, Y Geng, J Rigert, CD Fuller, AC Moreno… - medRxiv, 2022 - medrxiv.org
Background/objective Pain is the most common acute toxicity following radiation therapy
(RT) for head and neck cancer (HNC). The multifactorial origin of radiotherapy-induced pain …

[PDF][PDF] Single Nucleotide Polymorphisms as a Biomarker in the Assessment of Oral Mucositis in Head and Neck Cancer Patients: A Systematic Review

R Cavalieri, HF De Oliveira, TL de Souza… - 2023 - preprints.org
Single Nucleotide Polymorphisms (SNPs) are the most common type of genetic variation
found in individual's DNA sequences. SNPs can occur in both coding and non-coding …

Survival association of XRCC1 for patients with head and neck squamous cell carcinoma: A systematic review and meta-analysis

F Yang, L Zhou, J Chen, Y Luo, Y Wang - Frontiers in Genetics, 2023 - frontiersin.org
Background: Epidemiologic studies have demonstrated that X-ray repair cross-
complementary group 1 (XRCC1) is one of the susceptibility factors in head and neck …

[PDF][PDF] Prospective Evaluation of XRCC-1 as a Biopredictor for Survival Outcomes in Patients of Head and Neck Squamous Cell Carcinoma (HNSCC): A Meta-analysis

F Yang, L Zhou, Y Wang - 2021 - scholar.archive.org
Background: Epidemiologic studies have demonstrated that X-ray repair cross-
complementary group 1 (XRCC1) is one of the susceptibility factors in head and neck …