Ongoing efforts to improve antimicrobial utilization in hospitals among African countries and implications for the future

Z Saleem, B Godman, A Cook, MA Khan, SM Campbell… - Antibiotics, 2022 - mdpi.com
There are serious concerns with rising antimicrobial resistance (AMR) across countries
increasing morbidity, mortality and costs. These concerns have resulted in a plethora of …

Antibiotic use among hospitalized patients in Africa: a systematic review of point prevalence studies

U Abubakar, M Salman - Journal of Racial and Ethnic Health Disparities, 2024 - Springer
Background There is paucity of data describing the rate and quality indices of antibiotics
used among hospitalized patients at continental level in Africa. This systematic review …

Point prevalence of evidence-based antimicrobial use among hospitalized patients in sub-Saharan Africa: a systematic review and meta-analysis

MT Boltena, M Wolde, B Hailu, Z El-Khatib, V Steck… - Scientific Reports, 2024 - nature.com
Excessive and improper use of antibiotics causes antimicrobial resistance which is a major
threat to global health security. Hospitals in sub-Saharan Africa (SSA) has the highest …

Antibiotic utilization patterns for different wound types among surgical patients: findings and implications

Z Saleem, U Ahsan, A Haseeb, U Altaf, N Batool… - Antibiotics, 2023 - mdpi.com
Antimicrobial prophylaxis is effective in reducing the rate of surgical site infections (SSIs)
post-operatively. However, there are concerns with the extent of prophylaxis post …

Antibiotic use and adherence to the WHO AWaRe guidelines across 16 hospitals in Zambia: a point prevalence survey

JY Chizimu, S Mudenda, K Yamba… - JAC-Antimicrobial …, 2024 - academic.oup.com
Background The inappropriate use of antibiotics in hospitals contributes to the development
and spread of antimicrobial resistance (AMR). This study evaluated the prevalence of …

[HTML][HTML] Optimizing prophylactic antibiotic use among surgery patients in Ethiopian hospitals

G Alemkere, H Tadeg, W Getahun… - Journal of Infection and …, 2023 - Elsevier
Abstract Background Since 2018, the Ethiopian Ministry of Health (MOH) has been working
to institutionalize antimicrobial stewardship (AMS) programs across the country. The US …

Antibiotic use at a tertiary hospital in Tanzania: findings from a point prevalence survey

D Katyali, G Kawau, B Blomberg, J Manyahi - Antimicrobial Resistance & …, 2023 - Springer
Abstract Background In Tanzania, data on antibiotic use at the patient level is scarce, and
intervention measures to optimize antibiotic use and reduce antimicrobial resistance are …

Risk factors for colonization with multidrug-resistant bacteria in urban and rural communities in Kenya: an antimicrobial resistance in communities and hospitals …

MA Caudell, C Ayodo, T Ita, RM Smith… - Clinical Infectious …, 2023 - academic.oup.com
Background Colonization with antimicrobial-resistant bacteria increases the risk of drug-
resistant infections. We identified risk factors potentially associated with human colonization …

Distribution of ß-Lactamase Genes Among Multidrug-Resistant and Extended-Spectrum ß-Lactamase-Producing Diarrheagenic Escherichia coli from Under-Five …

T Zenebe, T Eguale, Z Desalegn… - Infection and Drug …, 2023 - Taylor & Francis
Purpose Escherichia coli strains that produce extended-spectrum ß-lactamase (ESBL) and
carbapenemase are among the major threats to global health. The objective of the present …

Antibiotic use among hospitalised patients in Sierra Leone: a national point prevalence survey using the WHO survey methodology

IF Kamara, J Kanu, A Maruta, BD Fofanah… - BMJ open, 2023 - bmjopen.bmj.com
Objective Inappropriate use of antibiotics is a major driver of antibiotic resistance. A few
studies conducted in Africa have documented that about half of hospitalised patients who …